D-myo-Inositol-1,4,5-triphosphate trisodium

Modify Date: 2024-01-07 10:19:26

D-myo-Inositol-1,4,5-triphosphate trisodium Structure
D-myo-Inositol-1,4,5-triphosphate trisodium structure
Common Name D-myo-Inositol-1,4,5-triphosphate trisodium
CAS Number 141611-10-1 Molecular Weight 486.04
Density N/A Boiling Point N/A
Molecular Formula C6H12Na3O15P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of D-myo-Inositol-1,4,5-triphosphate trisodium


D-myo-Inositol-1,4,5-triphosphate sodium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.

 Names

Name Trisodium (1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxy-1,2,4-cyclohexanet riyl tris[hydrogen (phosphate)]
Synonym More Synonyms

  Biological Activity

Description D-myo-Inositol-1,4,5-triphosphate sodium salt is the hexapotassium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
Related Catalog
In Vitro Second messenger D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3) is served as an inositol phosphate derivative. The dissociation constant (KD) for Pr55Gag complexed with D-myo-Inositol 1,4,5-trisphosphate (an inositol with divalent phosphate groups and devoid of lipid groups) is 2170 μM. The binding affinities of D-myo-Inositol 1,4,5-trisphosphate (KD=568 μM) and 1,3,4,5-IP4 (KD=526 μM) for matrix (MA) are almost identical[1].
References

[1]. Anraku K, et al. Highly sensitive analysis of the interaction between HIV-1 Gag and phosphoinositide derivatives based on surface plasmon resonance. Biochemistry. 2010 Jun 29;49(25):5109-16.  

 Chemical & Physical Properties

Molecular Formula C6H12Na3O15P3
Molecular Weight 486.04
Exact Mass 485.908203
PSA 298.89000

 Synonyms

D-myo-inositol-1,4,5-trisphosphate hexasodium
Trisodium (1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxy-1,2,4-cyclohexanetriyl tris[hydrogen (phosphate)]
1,2,3,4,5,6-Cyclohexanehexol, 1,2,4-tris(dihydrogen phosphate), sodium salt, (1R,2R,3S,4R,5R,6S)- (1:3)