N-Acetyl-D-galactosamine structure
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Common Name | N-Acetyl-D-galactosamine | ||
|---|---|---|---|---|
| CAS Number | 14215-68-0 | Molecular Weight | 221.208 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 595.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C8H15NO6 | Melting Point | 158-162 °C | |
| MSDS | Chinese | Flash Point | 313.9±30.1 °C | |
Use of N-Acetyl-D-galactosamineN-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets[1].N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin[2]. |
| Name | N-acetyl-D-galactosamine |
|---|---|
| Synonym | More Synonyms |
| Description | N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets[1].N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin[2]. |
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| Related Catalog | |
| In Vitro | N-Acetyl-D-galactosamine (GalNAc) (50nm; 4 hours) decreases the expression of occludin mRNA and claudin-3 mRNA by 1.6% and 2.7%[1]. N-Acetyl-D-galactosamine (GalNAc) (50nm; 4 hours) lowers the protein expression of occludin and claudin-3 by 4.3% and 7.2%, respectively[1]. RT-PCR[1] Cell Line: IPEC-J2 cell Concentration: 50 nM Incubation Time: 4 hours Result: Observed a slight reduction in mRNA expression of occludin and claudin-3. Western Blot Analysis[1] Cell Line: IPEC-J2 cell Concentration: 50 nM Incubation Time: 4 hours Result: Alleviated the damage of tight junction expressions at protein level. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 595.4±50.0 °C at 760 mmHg |
| Melting Point | 158-162 °C |
| Molecular Formula | C8H15NO6 |
| Molecular Weight | 221.208 |
| Flash Point | 313.9±30.1 °C |
| Exact Mass | 221.089935 |
| PSA | 119.25000 |
| LogP | -2.48 |
| Vapour Pressure | 0.0±3.8 mmHg at 25°C |
| Index of Refraction | 1.576 |
| InChIKey | OVRNDRQMDRJTHS-CBQIKETKSA-N |
| SMILES | CC(=O)NC1C(O)OC(CO)C(O)C1O |
| Storage condition | 2~8°C |
| Hazard Codes | Xi: Irritant; |
|---|---|
| Safety Phrases | S22-S24/25 |
| WGK Germany | 3 |
| N-[(3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl]acetamide |
| EINECS 217-321-9 |
| MFCD00065372 |
| D-Galactopyranose, 2-(acetylamino)-2-deoxy- |
| N-ACETEYL-D-GALACTOSAMINIDE |
| N-Acetyl-D-galactosamine |
| 2-(Acetylamino)-2-deoxy-D-galactopyranose |
| N-acelyl-D-glucosamine |
| 2-Acetamido-2-deoxy-D-galactose |
| N-Acetylchondrosamine |
| N-ACETYL-D-GALACTOSAMINIDE |
| N-((3R,4R,5R,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide |
| 2-Acetamido-2-deoxy-D-galactopyranose Hydrate |
| 2-Acetamido-2-deoxy-D-galactopyranose |
| ACETYL-D-GALACTOSAMINE |
| N-Acetyl-D-chondrosamine Hydrate |