Hederacoside C

Modify Date: 2024-01-02 16:38:23

Hederacoside C Structure
Hederacoside C structure
 Common Name Hederacoside C
CAS Number 14216-03-6 Molecular Weight 1221.378
Density 1.5±0.1 g/cm3 Boiling Point N/A
Molecular Formula C59H96O26 Melting Point 222ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07		 Signal Word Warning

 Use of Hederacoside C


Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects.

 Names

Name kalopanaxsaponin B
Synonym More Synonyms

 Hederacoside C Biological Activity

Description Hederacoside C is a principal bioactive pharmaceutical ingredient of Hedera helix leaf that can treat respiratory disorders, because of its expectorant, bronchodilator, antibacterial, and bronchospasmolytic effects.
Related Catalog
References

[1]. Rehman SU et al. An ultra-high-performance liquid chromatography-tandem mass spectrometric method for the determination ofhederacoside C, a drug candidate for respiratory disorder, in rat plasma. J Pharm Biomed Anal. 2016 Jun 24;129:90-95.

[2]. Kim JM et al. Pharmacokinetics of hederacoside C, an active ingredient in AG NPP709, in rats. Xenobiotica. 2013 Nov;43(11):985-92.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Melting Point 222ºC (dec.)(lit.)
Molecular Formula C59H96O26
Molecular Weight 1221.378
Exact Mass 1220.619019
PSA 412.82000
LogP 4.52
Index of Refraction 1.637
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 22-24/25
RIDADR UN 2811 6.1/PG 3
WGK Germany 3

 Synthetic Route

Kizuta saponin K11 structure

Kizuta saponin K11

CAS#:97240-03-4

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Hederacoside C Structure

Hederacoside C

CAS#:14216-03-6

Literature: Kizu; Kitayama; Nakatani; et al. Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3324 - 3329

 Articles7

More Articles
[Studies on the saponin constituents of Kalopanax septemlobus (Thunb.) koidz].

Yao Xue Xue Bao 25(1) , 29-34, (1990)

Two crystalline components I and II were isolated from the total saponin of Kalopanax septemlobus (Thunb.) koidz. Crystalline II was identified as kalopanax saponin A and I was named as Kalopanax sapo...

Triterpenoidal saponins from the bark of Kalopanax pictum var. typicum.

Arch. Pharm. Res. 14(1) , 19-24, (1991)

One new triterpenoidal saponin, saponin F(2) has been isolated from the bark of Kalopanax pictum Nakai var. typicum (Araliaceae), together with one known saponin, kizuta saponin K12 (1). On the basis ...

Antinociceptive and anti-rheumatoidal effects of Kalopanax pictus extract and its saponin components in experimental animals.

J. Ethnopharmacol. 79(2) , 199-204, (2002)

In the present study, we have attempted to elucidate the active components for rheumatoidal arthritis using chloroform (CHCl(3)), ethylacetate (EtOAc) and n-butanol (BuOH) fractions of the methanol ex...

 Synonyms

Hederacol
Akebia saponin pk
6-Deoxy-α-L-mannopyranosyl-(1->4)-β-D-glucopyranosyl-(1->6)-1-O-[(3β)-3-{[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-23-hydroxy-28-oxoolean-12-en-28-yl]-β-D-glucop yranose
Hederoside H1
Hederacauide D
Glycoside L-H2
kizutasaponin K12
Tauroside H2
hederasaponin C
Hederacoside C
β-D-Glucopyranose, O-6-deoxy-α-L-mannopyranosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-1-O-[(3β)-3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-28-oxoolean- 12-en-28-yl]-
Astrantiasaponin H
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