AC 186
Modify Date: 2024-01-27 17:35:16
AC 186 structure
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Common Name | AC 186 | ||
|---|---|---|---|---|
| CAS Number | 1421854-16-1 | Molecular Weight | 306.322 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 396.9±42.0 °C at 760 mmHg | |
| Molecular Formula | C18H17F3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 172.4±22.4 °C | |
Use of AC 186AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. AC-186 shows gender specific neuroprotection in a Parkinson’s Disease rat model[1]. |
| Name | AC-186 |
|---|---|
| Synonym | More Synonyms |
| Description | AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. AC-186 shows gender specific neuroprotection in a Parkinson’s Disease rat model[1]. |
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| Related Catalog | |
| Target |
ERβ:6 nM (EC50) ERα:5000 nM (EC50) |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 396.9±42.0 °C at 760 mmHg |
| Molecular Formula | C18H17F3O |
| Molecular Weight | 306.322 |
| Flash Point | 172.4±22.4 °C |
| Exact Mass | 306.123138 |
| LogP | 4.24 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.566 |
| 4-[4,4-Difluoro-1-(2-fluorophenyl)cyclohexyl]phenol |
| Phenol, 4-[4,4-difluoro-1-(2-fluorophenyl)cyclohexyl]- |
| AC-186 |