2-Chloro-4,6-dimethylnicotinonitrile

Modify Date: 2025-08-21 11:23:47

2-Chloro-4,6-dimethylnicotinonitrile structure	Common Name	2-Chloro-4,6-dimethylnicotinonitrile
	CAS Number	14237-71-9	Molecular Weight	166.608
	Density	1.2±0.1 g/cm3	Boiling Point	305.3±37.0 °C at 760 mmHg
	Molecular Formula	C₈H₇ClN₂	Melting Point	98-99°C
	MSDS	Chinese USA	Flash Point	138.5±26.5 °C
	Symbol	GHS05, GHS06	Signal Word	Danger

Name	2-Chloro-4,6-dimethylpyridine-3-carbonitrile
Synonym	More Synonyms

Density	1.2±0.1 g/cm3
Boiling Point	305.3±37.0 °C at 760 mmHg
Melting Point	98-99°C
Molecular Formula	C₈H₇ClN₂
Molecular Weight	166.608
Flash Point	138.5±26.5 °C
Exact Mass	166.029770
PSA	36.68000
LogP	2.06
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.547
InChIKey	RETJKTAVEQPNMH-UHFFFAOYSA-N
SMILES	Cc1cc(C)c(C#N)c(Cl)n1

2-Chloro-4,6-dimethylnicotinonitrile MSDS(Chinese)

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H315-H318-H335
Precautionary Statements	P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;
Risk Phrases	R25;R37/38;R41
Safety Phrases	S26-S36/37/39-S45
RIDADR	3276
Packaging Group	III
Hazard Class	6.1
HS Code	2933399090

3-Cyano-4,6-Dim...

CAS#:769-28-8

~97%

2-Chloro-4,6-di...

CAS#:14237-71-9

Literature: Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al. Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897

2‐imino‐4,6‐dim...

CAS#:60989-51-7

~96%

2-Chloro-4,6-di...

CAS#:14237-71-9

Literature: Waly, Mohamed A.; El-Hawary, Ibrahim I.; Hamama, Wafaa S.; Zoorob, Hanafi H. Journal of Heterocyclic Chemistry, 2013 , vol. 50, # SUPPL.1 p. E12-E17

N/A

CAS#:939125-32-3

~78%

2-Chloro-4,6-di...

CAS#:14237-71-9

Literature: Dmitrieva; Dyadyuchenko; Strelkov; Kaigorodova Chemistry of Heterocyclic Compounds, 2009 , vol. 45, # 9 p. 1047 - 1052

2,4-Pentandione

CAS#:123-54-6

2-Chloro-4,6-di...

CAS#:14237-71-9

Literature: Journal of Heterocyclic Chemistry, , vol. 50, # SUPPL.1 p. E12-E17

1,2-Dihydro-4,6...

CAS#:79927-21-2

2-Chloro-4,6-di...

CAS#:14237-71-9

Literature: Journal of the Indian Chemical Society, , vol. 73, # 2-3 p. 141 - 143

4,6-dimethyl-2-...

CAS#:54585-47-6

2-Chloro-4,6-di...

CAS#:14237-71-9

Literature: Journal of the Indian Chemical Society, , vol. 73, # 2-3 p. 141 - 143

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS

Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN

Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN

Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

Name: A screen for compounds that inhibit the activity of LtaS in Staphylococcus aureus
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
External Id: HMS979

Name: High throughput fluorescence intensity-based biochemical assay to screen for small mo...
Source: University of Pittsburgh Molecular Library Screening Center
Target: furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id: MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity

Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

Name: qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen
Source: NCGC
External Id: tdp43-p2-repeat

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