Ampicillin-d5

Modify Date: 2024-01-02 14:28:22

Ampicillin-d5 structure	Common Name	Ampicillin-d5
	CAS Number	1426173-65-0	Molecular Weight	354.436
	Density	1.5±0.1 g/cm3	Boiling Point	683.9±55.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₄D₅N₃O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	367.4±31.5 °C

Use of Ampicillin-d5

Ampicillin-d5 (D-(-)-α-Aminobenzylpenicillin-d5) is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].

Name	Ampicillin-d5
Synonym	More Synonyms

Description	Ampicillin-d5 (D-(-)-α-Aminobenzylpenicillin-d5) is the deuterium labeled Ampicillin. Ampicillin is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1][2][3].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Chopra SL, et al. Effect of Ampicillin on E. Coli of Swine Origin. Can J Comp Med Vet Sci. 1963 Sep;27(9):223-7. [3]. Lund B, et al. Ampicillin in portal and peripheral blood and bile after oral administration of ampicillin andpivampicillin. Eur J Clin Pharmacol. 1974;7(2):133-5. [4]. Lee KE, et al. The neuroprotective mechanism of ampicillin in a mouse model of transient forebrain ischemia. Korean J Physiol Pharmacol. 2016 Mar;20(2):185-92.

Density	1.5±0.1 g/cm3
Boiling Point	683.9±55.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₄D₅N₃O₄S
Molecular Weight	354.436
Flash Point	367.4±31.5 °C
Exact Mass	354.141022
LogP	1.35
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.675

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-amino-2-(phenyl-d5)acetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-

(2S,5R,6R)-6-{[(2R)-2-Amino-2-(2H5)phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

MFCD19704897

Ampicillin-d5

Use of Ampicillin-d5

Names

Ampicillin-d5 Biological Activity

Chemical & Physical Properties

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