PR-893

Modify Date: 2024-09-22 22:34:16

PR-893 Structure
PR-893 structure
Common Name PR-893
CAS Number 1426305-23-8 Molecular Weight 478.546
Density N/A Boiling Point N/A
Molecular Formula C23H34N4O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PR-893


A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.

 Names

Name PR-893

 PR-893 Biological Activity

Description A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.
References References 1. Parlati F, et al. Blood. 2009 Oct 15;114(16):3439-47. 2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209. View Related Products by Target Proteasome

 Chemical & Physical Properties

Molecular Formula C23H34N4O7
Molecular Weight 478.546
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