Hexadecylamine

Modify Date: 2025-08-26 12:56:22

Hexadecylamine Structure
Hexadecylamine structure
Common Name Hexadecylamine
CAS Number 143-27-1 Molecular Weight 241.456
Density 0.8±0.1 g/cm3 Boiling Point 321.8±5.0 °C at 760 mmHg
Molecular Formula C16H35N Melting Point 38-47ºC
MSDS Chinese USA Flash Point 140.6±0.0 °C
Symbol GHS05 GHS09
GHS05, GHS09
Signal Word Danger

 Names

Name 1-Hexadecylamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 321.8±5.0 °C at 760 mmHg
Melting Point 38-47ºC
Molecular Formula C16H35N
Molecular Weight 241.456
Flash Point 140.6±0.0 °C
Exact Mass 241.276947
PSA 26.02000
LogP 7.31
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.451
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ML9100000
CHEMICAL NAME :
1-Hexadecanamine
CAS REGISTRY NUMBER :
143-27-1
BEILSTEIN REFERENCE NO. :
1634065
LAST UPDATED :
199710
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C16-H35-N
MOLECULAR WEIGHT :
241.52
WISWESSER LINE NOTATION :
Z16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
40 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
DZZEA7 Deutsche Zahnaerztliche Zeitschrift. (Carl Hanser Verlag, Postfach 860420, D-8000 Munich 86, Fed. Rep. Ger.) V.1- 1946- Volume(issue)/page/year: 32,861,1977
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
10 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
DZZEA7 Deutsche Zahnaerztliche Zeitschrift. (Carl Hanser Verlag, Postfach 860420, D-8000 Munich 86, Fed. Rep. Ger.) V.1- 1946- Volume(issue)/page/year: 32,861,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83079 No. of Facilities: 13 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 125 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83079 No. of Facilities: 111 (estimated) No. of Industries: 7 No. of Occupations: 17 No. of Employees: 6933 (estimated) No. of Female Employees: 483 (estimated)

 Safety Information

Symbol GHS05 GHS09
GHS05, GHS09
Signal Word Danger
Hazard Statements H314-H400
Precautionary Statements P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S36/37/39-S45
RIDADR UN 3259
WGK Germany 2
RTECS ML9100000
Packaging Group III
Hazard Class 8.0
HS Code 29211980

 Synthetic Route

 Customs

HS Code 2921199090
Summary 2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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 Synonyms

palmitylamine
HDA
hexadecan-1-amine
Alamine 6
n-hexadecylmonoamine
AMINE C16
Hexadecylamine
Amine 16D
alamine6d
hexadecanamine
1-Aminohexadecane
AminePB
Cetylamin
EINECS 205-596-8
1-Hexadecanamine
armeen16d
Armeen 16
MFCD00008158
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