L 012 sodium salt

Modify Date: 2024-01-11 20:06:09

L 012 sodium salt structure	Common Name	L 012 sodium salt
	CAS Number	143556-24-5	Molecular Weight	310.671
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₈ClN₄NaO₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of L 012 sodium salt

L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2•−) and identify Nox inhibitors[1].

Name	L 012 sodium salt
Synonym	More Synonyms

Description	L 012 sodium salt a luminol-based chemiluminescent (CL) probe, is widely used in vitro and in vivo to detect NADPH oxidase (Nox)-derived superoxide (O2•−) and identify Nox inhibitors[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vitro	L-012 sodium salt, a chemical analog of luminol, gives rise to significantly higher luminescence yield and increased sensitivity as compared to other CL probes, lucigenin and MCLA[1].
In Vivo	L-012 sodium salt is well distributed in the mouse body and mediates a strong ROS/RNS-dependent luminescent signal in vivo and is useful for monitoring the development and regulation of inflammation in living organisms[2].
References	[1]. Zielonka J, et al. On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation. Free Radic Biol Med. 2013;65:1310-1314. [2]. Kielland A, et al. In vivo imaging of reactive oxygen and nitrogen species in inflammation using the luminescent probe L-012. Free Radic Biol Med. 2009;47(6):760-766.

Molecular Formula	C₁₃H₈ClN₄NaO₂
Molecular Weight	310.671
Exact Mass	310.023346

MFCD30378369

MFCD27991293

Pyrido[3,4-d]pyridazin-1(2H)-one, 8-amino-5-chloro-4-hydroxy-7-phenyl-, sodium salt (1:1)

Sodium 8-amino-5-chloro-1-oxo-7-phenyl-1,2-dihydropyrido[3,4-d]pyridazin-4-olate

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: L 012 Sodium Salt
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: L 012 sodium salt
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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L 012 sodium salt suppliers

Price: ￥1650/10 mM * 1 mL in DMSO

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