Protriptyline (N-methyl-d3) (hydrochloride)

Modify Date: 2025-09-10 12:28:32

Protriptyline (N-methyl-d3) (hydrochloride) Structure
Protriptyline (N-methyl-d3) (hydrochloride) structure
Common Name Protriptyline (N-methyl-d3) (hydrochloride)
CAS Number 1435934-21-6 Molecular Weight 266.40
Density N/A Boiling Point N/A
Molecular Formula C19H19D3ClN Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Protriptyline (N-methyl-d3) (hydrochloride)


Protriptyline (N-Methyl-d3) hydrochloride is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].

 Names

Name Protriptyline (N-methyl-d3) (hydrochloride)

  Biological Activity

Description Protriptyline (N-Methyl-d3) hydrochloride is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126(1):13-18.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Molecular Formula C19H19D3ClN
Molecular Weight 266.40
InChIKey OGQDIIKRQRZXJH-HGENJSHMSA-N
SMILES CNCCCC1c2ccccc2C=Cc2ccccc21.Cl
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Related Compounds: More...
Benzenemethanamine,N-(methyl-d3)-,hydrochloride
122025-10-9
Oxycodone D3
145225-02-1
para-Methoxymethamphetamine-d3 (hydrochloride)
1795033-58-7
Maprotiline-d3 (hydrochloride)
1329496-63-0
protriptyline
438-60-8
S-(N-Methyl-d3-carbamoyl)-L-cysteine
127633-26-5
Chlorantraniliprole-(N-methyl-d3)
1392493-28-5
Butyroyl N-(methyl-D3)-carnitine
203805-93-0
N-Methyl Carvedilol-d3 hydrochloride salt
1794766-62-3
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-(3,4-dimethylbenzenesulfonamido)butanoate
2248306-18-3
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(oxan-4-yl)propanoate
2248378-61-0
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 5-(oxan-4-yl)-1,2-oxazole-3-carboxylate
2248306-24-1
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2,4-dimethylimidazo[1,5-a]pyrimidine-8-carboxylate
2248284-01-5
rac-5-tert-butyl 3a-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) (3aR,6aS)-2,2-dioxo-hexahydro-1H-2lambda6-thieno[3,4-c]pyrrole-3a,5-dicarboxylate
2248281-86-7
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)methyl]-1-methyl-1H-pyrazole-4-carboxylate
2248374-91-4
rac-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2R,3R)-2-(1-methyl-1H-pyrazol-4-yl)oxane-3-carboxylate
2248331-01-1
rac-1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl (2R,3R)-2-(1-methyl-1H-imidazol-2-yl)oxane-3-carboxylate
2248306-32-1
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]acetate
2248301-00-8
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(butan-2-yl)-5-cyclopropyl-1H-pyrazole-4-carboxylate
2248306-35-4