Aldesulfone Sodium

Modify Date: 2026-07-02 08:20:44

Aldesulfone Sodium structure	Common Name	Aldesulfone Sodium
	CAS Number	144-75-2	Molecular Weight	448.44500
	Density	N/A	Boiling Point	857.3ºC at 760 mmHg
	Molecular Formula	C₁₄H₁₄N₂Na₂O₆S₃	Melting Point	N/A
	MSDS	N/A	Flash Point	472.3ºC

Use of Aldesulfone Sodium

Sulfoxone (Aldesulfone) disodium is an orally active sulphonamide antibiotic that is used against leprosy. Sulfoxone disodium can also be used in study of dermatitis herpetiformis[1][2].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Sulfoxone (Aldesulfone) disodium is an orally active sulphonamide antibiotic that is used against leprosy. Sulfoxone disodium can also be used in study of dermatitis herpetiformis[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Anti-infection >> Bacterial

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Boiling Point	857.3ºC at 760 mmHg
Molecular Formula	C₁₄H₁₄N₂Na₂O₆S₃
Molecular Weight	448.44500
Flash Point	472.3ºC
Exact Mass	447.98100
PSA	185.26000
LogP	3.97460
Vapour Pressure	2.64E-31mmHg at 25°C
InChIKey	AZBNFLZFSZDPQF-UHFFFAOYSA-L
SMILES	O=S([O-])CNc1ccc(S(=O)(=O)c2ccc(NCS(=O)[O-])cc2)cc1.[Na+].[Na+]
Stability	Stable. Incompatible with strong oxidizing agents.

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: PB0390100

CHEMICAL NAME :: Methanesulfinic acid, (sulfonylbis(p-phenyleneimino))di-, disodium salt

CAS REGISTRY NUMBER :: 144-75-2

LAST UPDATED :: 199606

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C14-H14-N2-O6-S3.2Na

MOLECULAR WEIGHT :: 448.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 30,317,1945

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 70,1268,1948

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 61,617,1939

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 30,317,1945

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 30,317,1945 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18900 mg/kg/21D-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

REFERENCE :: JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 30,317,1945

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code	2930909090

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signa...
Source: 824
Target: AR protein [Homo sapiens]
External Id: MDAN535

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1100

Name: qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in...
Source: NCGC
Target: TDP1 protein [Homo sapiens]
External Id: TDP1101

Name: qHTS assay to identify small molecule antagonists of the androgen receptor (AR) sign...
Source: 824
Target: N/A
External Id: MDAV150

Name: Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Source: NCGC
Target: N/A
External Id: TRND-SARS-CoV-2-cytotox-48hr

Name: qHTS assay for small molecules that induce genotoxicity in human embryonic kidney cel...
Source: 824
Target: RecName: Full=ATPase family AAA domain-containing protein 5; AltName: Full=Chromosome fragility-associated gene 1 protein
External Id: ELG271

Name: Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Source: NCGC
External Id: TRND-SARS-CoV-2-PP

Name: qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
Source: 824
Target: thyroid hormone receptor beta isoform 2 [Rattus norvegicus]
External Id: TRN186

Name: qHTS assay to identify small molecule antagonists of the thyroid receptor (TR) signal...
Source: 824
Target: N/A
External Id: TRV455

Name: Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screeni...
Source: NCGC
Target: N/A
External Id: CPF001

Total 59, Current Page 1 of 6

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Sodium sulfoxone

Aldapsone

Diazon

(4,4'-sulfonyl-dianilino)-bis-methanesulfinic acid,disodium-salt

Adesulfone sodium

(4,4'-Sulfonyl-dianilino)-bis-methansulfinsaeure,Dinatrium-Salz

Diamidin

Novotrone

Aldesulfone [Sodium]

SULFOXONE SODIUM

Diasone

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the uses of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: Main uses of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate: Sulfoxone (Aldesulfone) disodium is an orally active sulphonamide antibiotic that is used against leprosy. Sulfoxone disodium can also be used in study of dermatitis herpetiformis[1][2].

Q: What is the InChIKey of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: InChIKey of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is AZBNFLZFSZDPQF-UHFFFAOYSA-L.

Q: What is the molecular formula of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: Molecular formula of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is C14H14N2Na2O6S3.

Q: What is the English name of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: The English name of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate.

Q: What is the boiling point of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: Boiling point of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is 857.3ºC at 760 mmHg.

Q: What is the LogP of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: LogP of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is 3.97460.

Q: What English synonyms does disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate have?

A: English synonyms of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate: Sodium sulfoxone, Aldapsone, Diazon, (4,4'-sulfonyl-dianilino)-bis-methanesulfinic acid,disodium-salt, Adesulfone sodium, (4,4'-Sulfonyl-dianilino)-bis-methansulfinsaeure,Dinatrium-Salz, Diamidin, Novotrone, Aldesulfone [Sodium], SULFOXONE SODIUM, Diasone.

Q: What is the polar surface area (PSA) of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: Polar surface area (PSA) of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is 185.26000.

Q: What is the SMILES notation of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: SMILES notation of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is O=S([O-])CNc1ccc(S(=O)(=O)c2ccc(NCS(=O)[O-])cc2)cc1.[Na+].[Na+].

Q: What is the molecular weight of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate?

A: Molecular weight of disodium,[4-[4-(sulfinatomethylamino)phenyl]sulfonylanilino]methanesulfinate is 448.44500.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sulfoxone sodium
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Methanesulfinic acid,[sulfonylbis(4,1-phenyleneimino)]bis-, disodium salt (9CI)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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