Opiranserin hydrochloride structure
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Common Name | Opiranserin hydrochloride | ||
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CAS Number | 1440796-75-7 | Molecular Weight | 430.97 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C21H35ClN2O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of Opiranserin hydrochlorideOpiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain[1][2][3]. |
Name | Opiranserin hydrochloride |
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Description | Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain[1][2][3]. |
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Related Catalog | |
Target |
GlyT2:0.86 μM (IC50) 5-HT2A Receptor:1.3 μM (IC50) rP2X3:0.87 μM (IC50) |
References |
Molecular Formula | C21H35ClN2O5 |
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Molecular Weight | 430.97 |