1-Deazaadenosine
Modify Date: 2025-08-25 20:02:29
1-Deazaadenosine structure
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Common Name | 1-Deazaadenosine | ||
|---|---|---|---|---|
| CAS Number | 14432-09-8 | Molecular Weight | 266.25300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H14N4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 1-Deazaadenosine1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders[1][2]. |
| Name | 1-deazaadenosine |
|---|---|
| Synonym | More Synonyms |
| Description | 1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | 1-Deazaadenosine shows good activity in vitro as inhibitor of HeLa, KB, P388, and L1210 leukemia cell line growth, with ID50 values ranging from 0.34 μM (KB) to 1.8 μM (P388)[2]. |
| References |
| Molecular Formula | C11H14N4O4 |
|---|---|
| Molecular Weight | 266.25300 |
| Exact Mass | 266.10200 |
| PSA | 126.65000 |
| InChIKey | NVUDDRWKCUAERS-PNHWDRBUSA-N |
| SMILES | Nc1ccnc2c1ncn2C1OC(CO)C(O)C1O |
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| 7-Amino-3-(β-D-ribofuranosyl)imidazo[4,5-b]pyridine |
| 1-deaza-adenosine |
| 1-(7-amino-imidazo[4,5-b]pyridin-3-yl)-β-D-1-deoxy-ribofuranose |
| 1-Deazaadenosine |