1-[6-(Acetylamino)-6-deoxy-I(2)-D-glucopyranosyl]-4-chloro-3-[(4-cyclopropylphenyl)methyl]-1H-indole

Name: Effect on glucose AUC in Sprague-Dawley rat at 50 mg/kg, po administered as single do...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3792106

Name: Reduction of blood glucose level in Sprague-Dawley rat at 50 mg/kg, po administered a...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3792105

Name: Induction of glucosuria in Sprague-Dawley rat assessed as increase in glucose excreti...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3790123

Name: Half life in Sprague-Dawley rat at 1.1 mg/kg, iv administered via bolus injection by ...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3790127

Name: Selectivity ratio of EC50 for human SGLT1 expressed in CHO-K1 cells to EC50 for human...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3790126

Name: Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as reduction in [14C]AMG...
Source: ChEMBL
Target: Sodium/glucose cotransporter 1
External Id: CHEMBL3790125

Name: Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]AMG...
Source: ChEMBL
Target: Sodium/glucose cotransporter 2
External Id: CHEMBL3790124

Name: Half life in Sprague-Dawley rat at 1.1 mg/kg, po by LC-MS/MS analysis
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3790398

Name: AUC (0 to infinity) in Sprague-Dawley rat at 1.1 mg/kg, iv administered via bolus inj...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3790397

Name: Clearance in Sprague-Dawley rat at 1.1 mg/kg, iv administered via bolus injection mea...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL3790129