Murrayanol
Modify Date: 2024-01-02 18:01:30
Murrayanol structure
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Common Name | Murrayanol | ||
|---|---|---|---|---|
| CAS Number | 144525-81-5 | Molecular Weight | 363.49300 | |
| Density | 1.113±0.06 g/cm3(Predicted) | Boiling Point | 570.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C24H29NO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MurrayanolMurrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial[1]. |
| Name | Murrayanol |
|---|---|
| Synonym | More Synonyms |
| Description | Murrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial[1]. |
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| Related Catalog | |
| In Vitro | Murrayanol (Compound 2) 在抗炎试验中对人前列腺素 H 合酶同工酶 1 (hPGHS-1) 的 IC50 为 109 μg/mL，对 hPGHS-2 的 IC50 为 218 μg/mL[1]。 Murrayanol (Compound 2) 在 12.5 µg/mL 浓度下对埃及伊蚊显示 100% 的死亡率[1]。 当对酿酒酵母突变菌株进行测试时，Murrayanol (Compound 2) 在 50 µg/mL 浓度下完全抑制拓扑异构酶 I 和 II 活性[1]。 Murrayanol (Compound 2) 对克氏梭菌和大肠杆菌的 MIC1000 为 100 µg/mL，但对金黄色葡萄球菌和化脓性链球菌的 MIC100 为 25 µg/mL[1]。 |
| References |
| Density | 1.113±0.06 g/cm3(Predicted) |
|---|---|
| Boiling Point | 570.9±50.0 °C at 760 mmHg |
| Molecular Formula | C24H29NO2 |
| Molecular Weight | 363.49300 |
| Exact Mass | 363.22000 |
| PSA | 45.25000 |
| LogP | 6.57890 |
| 1-((E)-3,7-Dimethyl-octa-2,6-dienyl)-7-methoxy-6-methyl-9H-carbazol-2-ol |