TFMB-(S)-2-HG

Modify Date: 2024-01-02 01:12:00

TFMB-(S)-2-HG Structure
TFMB-(S)-2-HG structure
Common Name TFMB-(S)-2-HG
CAS Number 1445703-64-9 Molecular Weight 288.22
Density N/A Boiling Point N/A
Molecular Formula C13H11F3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TFMB-(S)-2-HG


TFMB-(S)-2-HG is a potent inhibitor of the 5'-methylcytosine hydroxylase TET2. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML)[1].

 Names

Name TFMB-(S)-2-HG

 TFMB-(S)-2-HG Biological Activity

Description TFMB-(S)-2-HG is a potent inhibitor of the 5'-methylcytosine hydroxylase TET2. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML)[1].
Related Catalog
References

[1]. Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013;339(6127):1621-1625.

 Chemical & Physical Properties

Molecular Formula C13H11F3O4
Molecular Weight 288.22