Phosphatidylserines (bovine)

Modify Date: 2024-01-09 22:56:17

Phosphatidylserines (bovine) Structure
Phosphatidylserines (bovine) structure
Common Name Phosphatidylserines (bovine)
CAS Number 1446756-47-3 Molecular Weight 792.075
Density 1.0±0.1 g/cm3 Boiling Point 816.3±75.0 °C at 760 mmHg
Molecular Formula C42H82NO10P Melting Point N/A
MSDS N/A Flash Point 447.5±37.1 °C

 Use of Phosphatidylserines (bovine)


Phosphatidylserine is a conserved anti-inflammatory and immunosuppressive signal that is highly dysregulated in the tumor microenvironment and autoimmune diseases. During apoptosis and cellular stress,the related disrupting enzymes Xkr8 and TMEM16 mediate Phosphatidylserine externalization. Phosphatidylserine externalization produces a "eat me" signal that initiates endocytosis and helps clear the body of apoptotic cells. When pathogens use Phosphatidylserine and apoptotic mimicry to evade host immune responses,targeting Phosphatidylserine strategies can stimulate immune activity[1].

 Names

Name Phosphatidylserines (bovine)
Synonym More Synonyms

 Phosphatidylserines (bovine) Biological Activity

Description Phosphatidylserine is a conserved anti-inflammatory and immunosuppressive signal that is highly dysregulated in the tumor microenvironment and autoimmune diseases. During apoptosis and cellular stress,the related disrupting enzymes Xkr8 and TMEM16 mediate Phosphatidylserine externalization. Phosphatidylserine externalization produces a "eat me" signal that initiates endocytosis and helps clear the body of apoptotic cells. When pathogens use Phosphatidylserine and apoptotic mimicry to evade host immune responses,targeting Phosphatidylserine strategies can stimulate immune activity[1].
Related Catalog
References

[1]. Birge RB, Boeltz S, Kumar S, Carlson J, Wanderley J, Calianese D, Barcinski M, Brekken RA, Huang X, Hutchins JT, Freimark B, Empig C, Mercer J, Schroit AJ, Schett G, Herrmann M. Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer. Cell Death Differ. 2016 Jun;23(6):962-78.  

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 816.3±75.0 °C at 760 mmHg
Molecular Formula C42H82NO10P
Molecular Weight 792.075
Flash Point 447.5±37.1 °C
Exact Mass 791.567627
LogP 16.13
Vapour Pressure 0.0±6.3 mmHg at 25°C
Index of Refraction 1.481

 Synonyms

Octadecanoic acid, (1R)-1-[[[[(2S)-2-amino-2-carboxyethoxy]hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
1,2-distearoyl-sn-glycero-3-phosphoserine
O-{[(2R)-2,3-Bis(stearoyloxy)propoxy](hydroxy)phosphoryl}-L-serine
MFCD00135635
Phosphatidylserine
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