Amgen-23

Modify Date: 2024-01-02 11:06:08

Amgen-23 Structure
Amgen-23 structure
Common Name Amgen-23
CAS Number 1448706-15-7 Molecular Weight 478.43
Density N/A Boiling Point N/A
Molecular Formula C23H25Cl2N3O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amgen-23


Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].

 Names

Name Amgen-23

 Amgen-23 Biological Activity

Description Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].
Related Catalog
Target

SphK1:20 nM (IC50)

SphK2:1.6 μM (IC50)

References

[1]. Gustin DJ, et al. Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16.

 Chemical & Physical Properties

Molecular Formula C23H25Cl2N3O2S
Molecular Weight 478.43
Storage condition -20°C
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