Hydrolyzed Fumonisin B1

Modify Date: 2024-01-11 15:48:45

Hydrolyzed Fumonisin B1 structure	Common Name	Hydrolyzed Fumonisin B1
	CAS Number	145040-09-1	Molecular Weight	405.61200
	Density	1.051±0.06 g/cm3(Predicted)	Boiling Point	593.8±50.0 °C(Predicted)
	Molecular Formula	C₂₂H₄₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Hydrolyzed Fumonisin B1

Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].

Name	(2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol
Synonym	More Synonyms

Description	Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Neurological Disease
References	[1]. Collins TF, et al. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 2006 Feb;44(2):161-9. [2]. Humpf HU, et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J Biol Chem. 1998 Jul 24;273(30):19060-4. [3]. Schmelz EM, et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.

Description

Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Neurological Disease

References

[1]. Collins TF, et al. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 2006 Feb;44(2):161-9.

[2]. Humpf HU, et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J Biol Chem. 1998 Jul 24;273(30):19060-4.

[3]. Schmelz EM, et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.

Density	1.051±0.06 g/cm3(Predicted)
Boiling Point	593.8±50.0 °C(Predicted)
Molecular Formula	C₂₂H₄₇NO₅
Molecular Weight	405.61200
Exact Mass	405.34500
PSA	127.17000
LogP	3.03150
Vapour Pressure	1.42E-16mmHg at 25°C
Storage condition	-20°C

Aminopentol

HFB1

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Hydrolyzed Fumonisin B1

Use of Hydrolyzed Fumonisin B1

Names

Hydrolyzed Fumonisin B1 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.