H-Met-Ser-OH

Modify Date: 2024-01-10 18:06:27

H-Met-Ser-OH Structure
H-Met-Ser-OH structure
Common Name H-Met-Ser-OH
CAS Number 14517-43-2 Molecular Weight 236.28900
Density N/A Boiling Point N/A
Molecular Formula C8H16N2O4S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of H-Met-Ser-OH


Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].

 Names

Name h-met-ser-oh
Synonym More Synonyms

 H-Met-Ser-OH Biological Activity

Description Methionylserine (H-MET-SER-OH) is a methionine- and serine-containing dipeptide. Methionylserine binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. Methionylserine inhibits ACE enzyme activity. Methionylserine can be used in the research of hypension[1][2].
Related Catalog
Target

hPEPT1[1], ACE[2].

References

[1]. Diana Højmark Omkvist, et al. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31.

[2]. Pan Wuguang, et al. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Patent WO2019006954.

 Chemical & Physical Properties

Molecular Formula C8H16N2O4S
Molecular Weight 236.28900
Exact Mass 236.08300
PSA 137.95000

 Safety Information

RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2930909090

 Customs

HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles1

More Articles
Neuraminidase inhibitors for influenza.

Biochem. Biophys. Res. Commun. 337 , 1125-32, (2005)

 Synonyms

L-methionine-L-serine
L-Met-L-Ser-OH
MET-SER
Met-Ser-OH
L-METHIONYL-L-SERINE
L-MET-SER
N-L-Methionyl-L-serine