FPI-1523 sodium

Modify Date: 2024-01-12 15:12:34

FPI-1523 sodium structure	Common Name	FPI-1523 sodium
	CAS Number	1452459-52-7	Molecular Weight	344.28
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₃N₄NaO₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FPI-1523 sodium

FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity[1].

Name	FPI-1523 sodium

Description	FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	β-lactamase[1]
In Vitro	FPI-1523 sodium inhibits K12 E. coli K12 and PBP2, with MIC and IC50 of 4 μg/mL and 0.4 μg/mL, respectively[1]. FPI-1523 sodium inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM)[1].
References	[1]. King AM, et, al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol. 2016 Apr 15;11(4):864-8.

Molecular Formula	C₉H₁₃N₄NaO₇S
Molecular Weight	344.28

DC Chemicals Limited
China
Product Name: FPI-1523 sodium
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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