FPI-1523 sodium
Modify Date: 2024-01-12 15:12:34
FPI-1523 sodium structure
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Common Name | FPI-1523 sodium | ||
|---|---|---|---|---|
| CAS Number | 1452459-52-7 | Molecular Weight | 344.28 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C9H13N4NaO7S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FPI-1523 sodiumFPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity[1]. |
| Name | FPI-1523 sodium |
|---|
| Description | FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity[1]. |
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| Related Catalog | |
| Target |
β-lactamase[1] |
| In Vitro | FPI-1523 sodium inhibits K12 E. coli K12 and PBP2, with MIC and IC50 of 4 μg/mL and 0.4 μg/mL, respectively[1]. FPI-1523 sodium inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM)[1]. |
| References |
| Molecular Formula | C9H13N4NaO7S |
|---|---|
| Molecular Weight | 344.28 |