N-1-Naphthylethylenediamine dihydrochloride

Modify Date: 2025-08-20 22:23:00

N-1-Naphthylethylenediamine dihydrochloride Structure
N-1-Naphthylethylenediamine dihydrochloride structure
Common Name N-1-Naphthylethylenediamine dihydrochloride
CAS Number 1465-25-4 Molecular Weight 259.175
Density N/A Boiling Point 370.7ºC at 760 mmHg
Molecular Formula C12H16Cl2N2 Melting Point 200 °C
MSDS Chinese USA Flash Point 209.7ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name N-(1-naphthyl)ethylenediamine dihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 370.7ºC at 760 mmHg
Melting Point 200 °C
Molecular Formula C12H16Cl2N2
Molecular Weight 259.175
Flash Point 209.7ºC
Exact Mass 258.069061
PSA 38.05000
LogP 4.58770
Vapour Pressure 1.08E-05mmHg at 25°C
Water Solubility soluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KV5330000
CHEMICAL NAME :
Ethylenediamine, N-(1-naphthyl)-, dihydrochloride
CAS REGISTRY NUMBER :
1465-25-4
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C12-H14-N2.2Cl-H
MOLECULAR WEIGHT :
259.20
WISWESSER LINE NOTATION :
L66J BM2Z &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
150 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
800 ug/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3681 No. of Facilities: 214 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 3452 (estimated) No. of Female Employees: 1660 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S36/37-S45-S37/39-S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS KV5330000
Packaging Group I; II; III
Hazard Class 6.1
HS Code 29215990

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2921590090
Summary 2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles81

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Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation.

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This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside)...

Modulation of cytochrome P450 2A5 activity by lipopolysaccharide: low-dose effects and non-monotonic dose-response relationship.

PLoS ONE 10(1) , e0117842, (2015)

Mouse cytochrome P450 (CYP) 2A5 is induced by inflammatory conditions and infectious diseases that down-regulate the expression and activity of most other CYP isoforms. Enhanced oxidative stress and n...

N-(1-naphthyl) ethylenediamine dinitrate: a new matrix for negative ion MALDI-TOF MS analysis of small molecules.

J. Am. Soc. Mass Spectrom. 23(9) , 1454-60, (2012)

An organic salt, N-(1-naphthyl) ethylenediamine dinitrate (NEDN), with rationally designed properties of a strong UV absorbing chromophore, hydrogen binding and nitrate anion donors, has been employed...

 Synonyms

N-(1-naphthyl)-ethylenediamine dihydrochloride
N-(1-naphthyl) ethylenediamine dihydrochloride
N-(1-Naphthyl)ethane-1,2-diamine dihydrochloride
N-(1-Naphthyl)ethylenediamine 2HCl
N-(1-Naphthyl)-1,2-ethanediamine dihydrochloride
N-(1-naphthyl)ethylene-1,2-diamine dihydrochloride
N-(1-Naphthyl)ethylenediamine,dihydrochlo
Bratton Marshall reagent
Monomethanolate
EINECS 215-981-2
N-(1-Naphthyl)ethylenediamine,dihydrochloride
MFCD00012556
1,2-Ethanediamine, N-1-naphthalenyl-, hydrochloride (1:2)
N-(1-Naphthyl)ethylenediamine dihydrochloride
MARSHALL'S REAGENT
N-(1-naphthyl)-1,2-ethylenediamine dihydrochloride
Bratton-Marshall Reage
N-(2-aminoethyl)naphthalen-1-amine dihydrochloride
Bratton-Marshall
N-(1-Naphthyl)ethyle
BRATTON'S REAGENT
N-1-Naphthylethylenediamine dihydrochloride
N1-(naphthalen-1-yl)ethane-1,2-diamine dihydrochloride
NED 2HCL
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