Olanexidine hydrochloride
Modify Date: 2024-01-18 17:48:51
Olanexidine hydrochloride structure
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Common Name | Olanexidine hydrochloride | ||
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| CAS Number | 146509-94-6 | Molecular Weight | 408.79700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H28Cl3N5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Olanexidine hydrochlorideOlanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli[1]. |
| Name | 1-carbamimidoyl-2-[(3,4-dichlorophenyl)methyl]-1-octylguanidine,hydrochloride |
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| Synonym | More Synonyms |
| Description | Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli[1]. |
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| Related Catalog | |
| In Vitro | Olanexidine 显示出以下杀菌机制：(i) 与细菌表面分子相互作用，如脂多糖和脂磷壁酸；(ii) 破坏脂质体的细胞膜，这是人工细菌膜模型；(iii) 增强大肠杆菌的膜通透性；(iv) 破坏金黄色葡萄球菌的膜完整性，以及 (v) 在相对高浓度 (≥160 μg/ml) 下使蛋白质变性[1]。 |
| References |
| Molecular Formula | C17H28Cl3N5 |
|---|---|
| Molecular Weight | 408.79700 |
| Exact Mass | 407.14100 |
| PSA | 88.99000 |
| LogP | 6.66640 |
| Olanexidine hydrochloride |
| OPB2045 |