arachidonoyl thio-pc

Modify Date: 2024-01-09 19:34:48

arachidonoyl thio-pc Structure
arachidonoyl thio-pc structure
Common Name arachidonoyl thio-pc
CAS Number 146797-82-2 Molecular Weight 784.164
Density N/A Boiling Point N/A
Molecular Formula C44H82NO6PS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of arachidonoyl thio-pc


Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.

 Names

Name arachidonoyl thio-pc
Synonym More Synonyms

 arachidonoyl thio-pc Biological Activity

Description Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.
Related Catalog

 Chemical & Physical Properties

Molecular Formula C44H82NO6PS
Molecular Weight 784.164
Exact Mass 783.560059
PSA 120.00000
LogP 12.05

 Synthetic Route

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arachidonoyl thio-pc Structure

arachidonoyl thio-pc

CAS#:146797-82-2

Literature: Murata; Ikoma; Achiwa Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 5 p. 1335 - 1336

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arachidonoyl thio-pc Structure

arachidonoyl thio-pc

CAS#:146797-82-2

Literature: Fuji, Masahiro; Watanabe, Fumihiko; Fujii, Yasuhiko; Hashizume, Hiroshi; Okuno, Takayuki; Shirahase, Kazuhiro; Teshirogi, Isao; Ohtani, Mitsuaki Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6804 - 6809

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arachidonoyl thio-pc Structure

arachidonoyl thio-pc

CAS#:146797-82-2

Literature: Fuji, Masahiro; Watanabe, Fumihiko; Fujii, Yasuhiko; Hashizume, Hiroshi; Okuno, Takayuki; Shirahase, Kazuhiro; Teshirogi, Isao; Ohtani, Mitsuaki Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6804 - 6809

~%

arachidonoyl thio-pc Structure

arachidonoyl thio-pc

CAS#:146797-82-2

Literature: Fuji, Masahiro; Watanabe, Fumihiko; Fujii, Yasuhiko; Hashizume, Hiroshi; Okuno, Takayuki; Shirahase, Kazuhiro; Teshirogi, Isao; Ohtani, Mitsuaki Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6804 - 6809

~%

arachidonoyl thio-pc Structure

arachidonoyl thio-pc

CAS#:146797-82-2

Literature: Fuji, Masahiro; Watanabe, Fumihiko; Fujii, Yasuhiko; Hashizume, Hiroshi; Okuno, Takayuki; Shirahase, Kazuhiro; Teshirogi, Isao; Ohtani, Mitsuaki Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6804 - 6809

~%

arachidonoyl thio-pc Structure

arachidonoyl thio-pc

CAS#:146797-82-2

Literature: Fuji, Masahiro; Watanabe, Fumihiko; Fujii, Yasuhiko; Hashizume, Hiroshi; Okuno, Takayuki; Shirahase, Kazuhiro; Teshirogi, Isao; Ohtani, Mitsuaki Journal of Organic Chemistry, 1997 , vol. 62, # 20 p. 6804 - 6809

 Synonyms

2-DEOXY-2-THIOARACHIDONOYLPHOSPHATIDYLCHOLINE
(2R)-3-(Hexadecyloxy)-2-[(5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoylsulfanyl]propyl 2-(trimethylammonio)ethyl phosphate
Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-[[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]thio]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
2-DEOXY-2-THIO ARACHIDONOYL PC
1-O-hexadecyl-2-thioarachidonyl-2-deoxy-sn-glycero-3-phosphocholine
(2R)-3-(Hexadecyloxy)-2-[(5Z,8Z,11E,14E)-5,8,11,14-icosatetraenoylsulfanyl]propyl 2-(trimethylammonio)ethyl phosphate
1-Hexadecyl-2-arachidonoylthio-2-deoxy-sn-glycero-3-phosphorylcholine
1-hexadecyl-2-arachidonoylthio-2-deoxyglycero-3-phosphorylcholine
Ethanaminium, 2-[[[(2R)-3-(hexadecyloxy)-2-[[(5Z,8Z,11E,14E)-1-oxo-5,8,11,14-eicosatetraen-1-yl]thio]propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Thiopc