Arachidonic acid

Modify Date: 2025-08-21 11:52:00

Arachidonic acid structure	Common Name	Arachidonic acid
	CAS Number	506-32-1	Molecular Weight	304.467
	Density	0.9±0.1 g/cm3	Boiling Point	407.5±0.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₃₂O₂	Melting Point	−49 °C(lit.)
	MSDS	Chinese USA	Flash Point	336.3±18.0 °C

Use of Arachidonic acid

Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.

Name	arachidonic acid
Synonym	More Synonyms

Description	Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Inflammation/Immunology
Target	Human Endogenous Metabolite
In Vivo	Arachidonic acid (ARA) is converted into various lipid mediators, such as prostaglandin E2 (PGE2), which is involved in the development of rheumatoid arthritis (RA)[1].
References	[1]. Tateishi N, et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. Lipids Health Dis. 2015 Jan 16;14:3.

Density	0.9±0.1 g/cm3
Boiling Point	407.5±0.0 °C at 760 mmHg
Melting Point	−49 °C(lit.)
Molecular Formula	C₂₀H₃₂O₂
Molecular Weight	304.467
Flash Point	336.3±18.0 °C
Exact Mass	304.240234
PSA	37.30000
LogP	6.91
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.501
Water Solubility	PRACTICALLY INSOLUBLE

Arachidonic acid MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CE6675000

CHEMICAL NAME :: Arachidonic acid

CAS REGISTRY NUMBER :: 506-32-1

LAST UPDATED :: 199504

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C20-H32-O2

MOLECULAR WEIGHT :: 304.52

WISWESSER LINE NOTATION :: QV4U3U3U3U6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 39200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 80 ug/kg

SEX/DURATION :: female 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 320 umol/L

REFERENCE :: PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 27,95,1986 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,481,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1132 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 79 (estimated) No. of Female Employees: 60 (estimated)

Personal Protective Equipment	Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes	F
Risk Phrases	R19
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	CE6675000
Packaging Group	I; II; III
Hazard Class	6.1
HS Code	2916190090

Precursor 9
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DownStream 10
CAS#:54397-85-2 PhD CAS#:363-24-6 Dinoprostone CAS#:54397-83-0 12S-HETE CAS#:4312-99-6 1-Octen-3-one
CAS#:3391-86-4 Oct-1-en-3-ol CAS#:20664-46-4 (Z)-2-octen-1-al CAS#:66-25-1 Hexanal CAS#:506-30-9 Arachidic acid
CAS#:41598-07-6 Prostaglandin D2 CAS#:551-11-1 tromethamine

HS Code	2916190090
Summary	2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

Omega-3 fatty acids, EPA and DHA induce apoptosis and enhance drug sensitivity in multiple myeloma cells but not in normal peripheral mononuclear cells.

J. Nutr. Biochem. 25(12) , 1254-62, (2014)

The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been shown to enhance the effect of chemotherapeutic drugs in clinical studies in cancer patients an...

Cryopreservation prevents iron-initiated highly unsaturated fatty acid loss during storage of human blood on chromatography paper at -20°C.

J. Nutr. 145(3) , 654-60, (2015)

Fingertip prick whole blood collection on chromatography paper is amenable to high-throughput fatty acid (FA) profiling for large clinical and field studies. However, sample storage is problematic bec...

Reduced filaggrin expression is accompanied by increased Staphylococcus aureus colonization of epidermal skin models.

Clin. Exp. Allergy 44(12) , 1515-24, (2014)

Atopic dermatitis is an inflammatory skin disease that is characterized by a reduced skin barrier function, reduced filaggrin (FLG) expression as well as increased colonization by Staphylococcus aureu...

(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid

Immunocytophyte

eicosatetraenoic acid

MFCD00004417

PUFA 20:4n-6

ARACHIDONIC ACID(RG)

5,8,11,14-Icosatetraenoic Acid

Arachidonic acid

Hydrazinecarboselenoamide

ARA

5,8,11,14-Eicosatetraenoic Acid

(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid

C20:4 (cis-5,8,11,14)

20:4n-6

5,8,11,14-all-cis-Eicosatetraenoic acid

5,8,11,14-Eicosatetraenoic acid, (all-Z)-

5,8,11,14-Eicosatetraenoic acid, (5Z,8Z,11Z,14Z)-

Arachidonate

(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid

Arachidonic

EINECS 208-033-4

(all-Z)-5,8,11,14-Eicosatetraenoic acid

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Price: ￥550/10 mM * 1 mL in DMSO

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Arachidonic acid

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