IMP2-IN-1

Modify Date: 2024-01-09 12:13:30

IMP2-IN-1 Structure
IMP2-IN-1 structure
Common Name IMP2-IN-1
CAS Number 1480482-51-6 Molecular Weight 401.34
Density N/A Boiling Point N/A
Molecular Formula C21H14F3NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IMP2-IN-1


IMP2-IN-1 (compound 4) is a potent IMP2 inhibitor with IC50 value of 81.3~127.5 for IMP2 RNA sequence. IMP2-IN-1 reduces IMP2 in SW480 cells. IMP2-IN-1 significantly reduces the viability of both differentiated and non-differentiated Huh7 cells[1].

 Names

Name IMP2-IN-1

 IMP2-IN-1 Biological Activity

Description IMP2-IN-1 (compound 4) is a potent IMP2 inhibitor with IC50 value of 81.3~127.5 for IMP2 RNA sequence. IMP2-IN-1 reduces IMP2 in SW480 cells. IMP2-IN-1 significantly reduces the viability of both differentiated and non-differentiated Huh7 cells[1].
Related Catalog
Target

IC50: 81.3~127.5 μM (IMP2)[1]

References

[1]. Dahlem C, et al. First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy. ACS Chem Biol. 2022;17(2):361-375.

 Chemical & Physical Properties

Molecular Formula C21H14F3NO4
Molecular Weight 401.34