S-15176 difumarate salt
S-15176 difumarate salt structure
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Common Name | S-15176 difumarate salt | ||
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| CAS Number | 148913-55-7 | Molecular Weight | 776.93300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C39H56N2O12S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
| Name | (E)-but-2-enedioic acid,2,6-ditert-butyl-4-[3-[4-[(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl]propylsulfanyl]phenol |
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| Synonym | More Synonyms |
| Molecular Formula | C39H56N2O12S |
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| Molecular Weight | 776.93300 |
| Exact Mass | 776.35500 |
| PSA | 228.90000 |
| LogP | 5.61240 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| RIDADR | NONH for all modes of transport |
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S-15176 inhibits mitochondrial permeability transition via a mechanism independent of its antioxidant properties.
Eur. J. Pharmacol. 468 , 93-101, (2003) Mitochondrial Ca(2+) accumulation can induce a sudden increase in the permeability of the inner membrane. This phenomenon is due to the generation of a large nonselective ion channel, termed the perme... |
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Inhibition of mitochondrial carnitine palmitoyltransferase-1 by a trimetazidine derivative, S-15176.
Pharmaceut. Res. 44 , 99-104, (2001) The purpose of this study was to investigate the possible effect of the trimetazidine derivative S-15176 on carnitine palmitoyltransferase1 (CPT-1) activity in rat heart and liver mitochondria. S-1517... |
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S-15176 reduces the hepatic injury in rats subjected to experimental ischemia and reperfusion.
Eur. J. Pharmacol. 406 , 281-292, (2000) The protective effect of N-[(3, 5-di-tertiobutyl-4-hydroxy-1-thiophenyl)]-3-propyl-N'-(2,3, 4-trimethoxybenzyl)piperazine (S-15176) on liver injury induced by warm ischemia-reperfusion was investigate... |
| N-[(3,5-Di-tert-butyl-4-hydroxy-1-thiophenyl)]-3-propyl-N inverted exclamation marka-(2,3,4-trimethoxybenzyl)piperazine difumarate salt |