naftalofos

Modify Date: 2024-01-21 18:55:00

naftalofos Structure
naftalofos structure
Common Name naftalofos
CAS Number 1491-41-4 Molecular Weight 349.275
Density 1.4±0.1 g/cm3 Boiling Point 487.3±28.0 °C at 760 mmHg
Molecular Formula C16H16NO6P Melting Point 115-116ºC
MSDS Chinese USA Flash Point 248.5±24.0 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of naftalofos


Naftalofos is an insecticide and an anthelmintic. Naftalofos represents an effective therapeutic alternative for incorporation into worm control programmes.

 Names

Name naftalofos
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 487.3±28.0 °C at 760 mmHg
Melting Point 115-116ºC
Molecular Formula C16H16NO6P
Molecular Weight 349.275
Flash Point 248.5±24.0 °C
Exact Mass 349.071533
PSA 93.64000
LogP 2.01
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.612

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK5775000
CHEMICAL NAME :
Naphthalimide, N-hydroxy-, diethyl phosphate
CAS REGISTRY NUMBER :
1491-41-4
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C16-H16-N-O6-P
MOLECULAR WEIGHT :
349.30
WISWESSER LINE NOTATION :
T666 1A M CVNVJ DOPO&O2&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
70 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,45,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARSIM* Agricultural Research Service, USDA Information Memorandum. (Beltsville, MD 20705) Volume(issue)/page/year: 20,3,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
43300 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,49,1967
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 17,108,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - chicken
DOSE/DURATION :
1960 mg/kg/2W-C
TOXIC EFFECTS :
Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 11,49,1967 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 46,1,1973

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H310
Precautionary Statements P280-P301 + P310-P302 + P350-P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T: Toxic;
Risk Phrases R24/25
Safety Phrases 36/37-45
RIDADR UN 2783
RTECS QK5775000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles9

More Articles
Phenobarbital induction and chemical synergism demonstrate the role of UDP-glucuronosyltransferases in detoxification of naphthalophos by Haemonchus contortus larvae.

Antimicrob. Agents Chemother. 58(12) , 7475-83, (2014)

We used an enzyme induction approach to study the role of detoxification enzymes in the interaction of the anthelmintic compound naphthalophos with Haemonchus contortus larvae. Larvae were treated wit...

The efficacy of trichlorphon and naphthalophos against multiple anthelmintic-resistant nematodes of naturally infected sheep in Argentina.

Parasitol. Res. 109 Suppl 1 , S139-48, (2011)

An anthelmintic efficacy trial was conducted in sheep harbouring anthelmintic-resistant worms in Argentina. Seventy lambs were selected from a flock that had been grazed on pastures infected with tric...

Pharmacology of anthelmintic resistance.

Parasitology 113 Suppl , S201-16, (1996)

Anthelmintic resistance has compromised the control of nematode parasites in several animal-based industries. Studies of resistance have not only improved our understanding of this phenomenon but also...

 Synonyms

1H-Benz[de]isoquinoline-1,3(2H)-dione, 2-[(diethoxyphosphinyl)oxy]-
O,O-Diethyl O-Naphthaloximide Phosphate
1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl diethyl phosphate
Naftalofosum
diethyl naphthalimidooxyphosphonate
Phtalophos
Rametin
EINECS 216-078-6
O,O-Diethyl N-hydroxynaphthalimide phosphate,Naphthalophos
Bayer S940
(1,3-dioxobenzo[de]isoquinolin-2-yl) diethyl phosphate
2-[(Diethoxyphosphoryl)oxy]-1H-benzo[de]isoquinoline-1,3(2H)-dione
phthalophos
Maretin
2-[(Diethoxyphosphinyl)oxy]-1H-benz[de]isoquinoline-1,3(2H)-dione
naftalofosum [INN_la]
Phosphorsaeure-(1,3-dioxo-2,3-dihydro-1H-benz[d,e]isochinolyl-(2)-ester)-diethylester
naftalofos
naphthalophos
Bayer 9002
Rawetin
MFCD00864515
Top Suppliers:I want be here






Get all suppliers and price by the below link:

naftalofos suppliers

naftalofos price