L 731,735

Modify Date: 2024-01-19 13:30:18

L 731,735 Structure
L 731,735 structure
Common Name L 731,735
CAS Number 149756-20-7 Molecular Weight 420.61000
Density 1.113g/cm3 Boiling Point 662.6ºC at 760mmHg
Molecular Formula C19H40N4O4S Melting Point N/A
MSDS N/A Flash Point 354.5ºC

 Use of L 731,735


L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research[1].

 Names

Name (2S)-2-[[(2S,3S)-2-[[2-[(2-amino-3-sulfanylpropyl)amino]-3-methylpentyl]amino]-3-methylpentanoyl]amino]-4-hydroxybutanoic acid
Synonym More Synonyms

 L 731,735 Biological Activity

Description L-731735 is a selective FPTase inhibitor that can inhibit ras-dependent cell transformation. L-731735 can be used in cancer research[1].
Related Catalog
References

[1]. Kohl NE, et al. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 1993 Jun 25;260(5116):1934-7.  

 Chemical & Physical Properties

Density 1.113g/cm3
Boiling Point 662.6ºC at 760mmHg
Molecular Formula C19H40N4O4S
Molecular Weight 420.61000
Flash Point 354.5ºC
Exact Mass 420.27700
PSA 179.00000
LogP 2.52630
Vapour Pressure 2.24E-20mmHg at 25°C
Index of Refraction 1.521

 Synonyms

N-(2-(3-Mercapto-2-aminopropylamino)-3-methylpentyl)isoleucyl-homoserine
L-Homoserine,N-(N-(2-((2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-L-isoleucyl)-,(2S-(2R*(S*),3S*))
L 731,735
Nampamp-ile-hse
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