Nec-3a

Modify Date: 2025-08-26 00:24:56

Nec-3a Structure
Nec-3a structure
 Common Name Nec-3a
CAS Number 1504558-72-8 Molecular Weight 438.37
Density N/A Boiling Point N/A
Molecular Formula C21H18F4N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Nec-3a


Nec-3a is a Necrostatin-3 analogue. Nec-3a is a RIP1 inhibitor (IC50: 0.44 μM). Nec-3a inhibits the autophosphorylation activity of the RIP1 kinase domain[1].

 Names

Name Nec-3a

 Nec-3a Biological Activity

Description Nec-3a is a Necrostatin-3 analogue. Nec-3a is a RIP1 inhibitor (IC50: 0.44 μM). Nec-3a inhibits the autophosphorylation activity of the RIP1 kinase domain[1].
Related Catalog
Target

RIPK1:0.44 μM (IC50)

References

[1]. Xie T, et al. Structural basis of RIP1 inhibition by necrostatins. Structure. 2013 Mar 5;21(3):493-9.  

 Chemical & Physical Properties

Molecular Formula C21H18F4N2O4
Molecular Weight 438.37
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here
Related Compounds: More...
Necrostatin-34
375835-43-1
3,3a,4,4a,5,7a,8,8a-octahydro-3-methyl-4,8-methano-2H-indeno[5,6-b]furan-2-one
93893-94-8
3,3a,4,4a,7,7a,8,8a-octahydro-3-methyl-4,8-methano-2H-indeno[5,6-b]furan-2-one
93893-92-6
ethyl 3a-hydroxy-2-oxo-3H-cyclopenta[l]phenanthrene-1-carboxylate
72471-15-9
3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one
5650-67-9
cis-3a,4,5,6,7,7a-hexahydro-2-phenylbenzoxazole
57437-13-5
3,3a,6,6a-Tetrahydro-1H-cyclopenta[c]furan-1-one
344324-25-0
2-(3a,7a-dimethyl-1,3,4,5,6,7-hexahydro-octahydro-1H-4,7-epoxyisoindol-2-yl)ethyl-trimethylazanium
7150-86-9
(7aS)-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione
117307-09-2
N-(2,6-dimethylphenyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
1049514-60-4
5-((3-methoxybenzyl)oxy)-2-(4-(pyridin-2-yl)piperazine-1-carbonyl)pyridin-4(1H)-one
1021261-96-0
5-chloro-N-(4-((6-isopropoxy-2-methylpyrimidin-4-yl)amino)phenyl)-2-methoxybenzamide
946234-51-1
6-Benzyl-3-(2,3-difluorophenyl)[1,2,4]triazolo[3,4-a]phthalazine
1010896-38-4
2-(5,6,7,8-tetrahydronaphthalen-2-yl)-1H-indole
101733-50-0
2-(6-benzyl-1,1-dioxido-1,2,6-thiadiazinan-2-yl)-N-(5-chloro-2-methoxyphenyl)acetamide
946238-50-2
(3-Methoxyphenyl)[3-(4-methoxyphenyl)thiomorpholin-4-yl]methanone
1040703-40-9
(5-methoxy-1,2-dimethyl-1H-indol-3-yl)[3-([1,2,4]triazolo[4,3-a]pyridin-3-yl)piperidin-1-yl]methanone
1081136-47-1
5,9,10-trimethyl-2-(2,3,4-trimethoxyphenyl)-2,3-dihydro-4H,8H-pyrano[2,3-f]chromene-4,8-dione
1010924-02-3
N-[4-(acetylamino)phenyl]-1-[3-(propan-2-yl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidine-3-carboxamide
1144432-35-8
Chemsrc provides Nec-3a(CAS#:1504558-72-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Nec-3a are included as well.>> amp version: Nec-3a

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved