1-(4-chlorophenyl)-2-methylpropan-2-amine hydrochloride

1-(4-chlorophenyl)-2-methylpropan-2-amine hydrochloride structure	Common Name	1-(4-chlorophenyl)-2-methylpropan-2-amine hydrochloride
CAS Number	151-06-4	Molecular Weight	220.139
Density	N/A	Boiling Point	255.8ºC at 760mmHg
Molecular Formula	C₁₀H₁₅Cl₂N	Melting Point	N/A
MSDS	N/A	Flash Point	127ºC

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Boiling Point	255.8ºC at 760mmHg
Molecular Formula	C₁₀H₁₅Cl₂N
Molecular Weight	220.139
Flash Point	127ºC
Exact Mass	219.058151
PSA	26.02000
LogP	4.12210
Vapour Pressure	0.016mmHg at 25°C
InChIKey	WEJDYJKJPUPMLH-UHFFFAOYSA-N
SMILES	CC(C)(N)Cc1ccc(Cl)cc1.Cl

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SH1225000

CHEMICAL NAME :: Phenethylamine, p-chloro-alpha,alpha-dimethyl-, hydrochloride

CAS REGISTRY NUMBER :: 151-06-4

LAST UPDATED :: 199503

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C10-H14-Cl-N.Cl-H

MOLECULAR WEIGHT :: 220.16

WISWESSER LINE NOTATION :: ZX1&1&1R DG &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 5,247,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 144 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal)

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 17,121,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 225 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,711,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 88 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 5,247,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 225 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - excitement Skin and Appendages - hair

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 4,37,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - changes in motor activity (specific assay) Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 137,365,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 840 mg/kg/2W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - changes in lung weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Metabolism (Intermediary) - lipids including transport

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 65,100,1982 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 27 mg/kg

SEX/DURATION :: female 12-22 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - physical

REFERENCE :: VAAZA2 Virchows Archiv, Abteilung B: Cell Pathology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1968- Volume(issue)/page/year: 39,59,1982

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 150 mg/kg

SEX/DURATION :: female 16-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 1,31,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 150 mg/kg

SEX/DURATION :: female 16-20 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

REFERENCE :: EXMPA6 Experimental and Molecular Pathology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1962- Volume(issue)/page/year: 38,310,1983

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 21 mg/kg

SEX/DURATION :: female 32-68 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - physical

REFERENCE :: VAAZA2 Virchows Archiv, Abteilung B: Cell Pathology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1968- Volume(issue)/page/year: 39,59,1982

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

HS Code	2921499090

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 2
CAS#:874-72-6 4-CHLOROBENZYLM... CAS#:5468-97-3 1-(4-Chlorophen...
DownStream 1
CAS#:51026-12-1 2-[1-(4-chlorop...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2921499090
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Desopimon

1-(4-chlorophenyl)-2-methylpropan-2-amine,hydrochloride

1-(4-Chlorophenyl)-2-methyl-2-propanamine hydrochloride (1:1)

Lukofen hydrochloride

1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride (1:1)

Phenethylamine, 4-chloro-α,α-dimethyl-, hydrochloride

α,α-Dimethyl-p-chlorophenethylamine hydrochloride

4-Chloro-α,α-dimethylphenethylamine hydrochloride

Benzeneethanamine, 4-chloro-α,α-dimethyl-, hydrochloride

p-Chloro-α,α-dimethylphenethylamine hydrochloride

chlorphentermine hydrochloride

Apsedon

a,a-Dimethyl-p-chlorophenethylamine Hydrochloride

Benzeneethanamine, 4-chloro-α,α-dimethyl-, hydrochloride (1:1)

Phenethylamine, p-chloro-α,α-dimethyl-, hydrochloride

Dezopimon

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the polar surface area (PSA) of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: Polar surface area (PSA) of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is 26.02000.

Q: What is the CAS number of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: CAS number of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is 151-06-4.

Q: What is the molecular formula of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: Molecular formula of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is C10H15Cl2N.

Q: What is the SMILES notation of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: SMILES notation of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is CC(C)(N)Cc1ccc(Cl)cc1.Cl.

Q: What is the boiling point of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: Boiling point of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is 255.8ºC at 760mmHg.

Q: What is the English name of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: The English name of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride.

Q: What are the downstream products of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: Related downstream products(CAS) of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride: 51026-12-1.

Q: What is the molecular weight of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: Molecular weight of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is 220.139.

Q: What is the InChIKey of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: InChIKey of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is WEJDYJKJPUPMLH-UHFFFAOYSA-N.

Q: What is the LogP of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride?

A: LogP of 1-(4-Chlorophenyl)-2-methylpropan-2-amine hydrochloride is 4.12210.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

1-(4-chlorophenyl)-2-methylpropan-2-amine hydrochloride

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Precursor & DownStream

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Bioassay

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