CL264

Modify Date: 2024-01-13 14:22:56

CL264 Structure
CL264 structure
Common Name CL264
CAS Number 1510712-69-2 Molecular Weight 413.43
Density 1.427±0.06 g/cm3(Predicted) Boiling Point N/A
Molecular Formula C19H23N7O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL264


CL264 is a TLR7-specific agonist for innate immune signals research[1].

 Names

Name CL264

 CL264 Biological Activity

Description CL264 is a TLR7-specific agonist for innate immune signals research[1].
Related Catalog
Target

TLR7

In Vitro Toll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7 is expressed predominantly in plasmacytoid dendritic cells (pDCs), macrophages and B cells. Many TLR7 modulators are interferon inducers, anti-cancer agents, anti-infectious agents, therapeutic agents for immunological diseases and vaccine adjuvants[1].
References

[1]. Butterfield JSS, et al. TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer. Hum Gene Ther Methods. 2019 Jun;30(3):81-92.

 Chemical & Physical Properties

Density 1.427±0.06 g/cm3(Predicted)
Molecular Formula C19H23N7O4
Molecular Weight 413.43
Storage condition 2-8°C