4'-Hydroxy-2,4-dimethoxychalcone
Modify Date: 2024-01-10 10:29:33
4'-Hydroxy-2,4-dimethoxychalcone structure
|
Common Name | 4'-Hydroxy-2,4-dimethoxychalcone | ||
|---|---|---|---|---|
| CAS Number | 151135-64-7 | Molecular Weight | 284.306 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 500.1±50.0 °C at 760 mmHg | |
| Molecular Formula | C17H16O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 185.8±23.6 °C | |
Use of 4'-Hydroxy-2,4-dimethoxychalcone4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2]. |
| Name | (2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one |
|---|---|
| Synonym | More Synonyms |
| Description | 4'-Hydroxy-2,4-dimethoxychalcone is a natural chalcone derivatives in the red herbal resin of Dracaena cochinchinensis. 4'-Hydroxy-2,4-dimethoxychalcone displays a wide range of biological activities including antimalarial, antiprotozoal, antibacterial, antifungal activity[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | 4'-Hydroxy-2,4-dimethoxychalcone (compound 2) is against P. falciparum D6 (IC50=4.2 μM) and W2 (IC50=4.8 μM)[1]. |
| In Vivo | 4'-Hydroxy-2,4-dimethoxychalcone (compound 2; oral; 160 mg/kg) has a T1/2 of 1.94 hours, a Cmax of 158 ng/mL and an AUC of 384 ng•h/mL in four- to five-week-old ICR mice[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 500.1±50.0 °C at 760 mmHg |
| Molecular Formula | C17H16O4 |
| Molecular Weight | 284.306 |
| Flash Point | 185.8±23.6 °C |
| Exact Mass | 284.104858 |
| LogP | 3.48 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.614 |
| Storage condition | 2-8℃ |
| 2-Propen-1-one, 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)-, (2E)- |
| (2E)-3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one |
| (2E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-2-propen-1-one |