(R)-Plevitrexed

Modify Date: 2025-08-27 09:48:35

(R)-Plevitrexed structure	Common Name	(R)-Plevitrexed
	CAS Number	153537-74-7	Molecular Weight	532.52600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₅FN₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (R)-Plevitrexed

(R)-Plevitrexed ((R)-ZD 9331; (R)-BGC9331) is a less active enantiomer of Plevitrexed[1]. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor[2].

Name	(2R)-2-[[4-[(2,7-dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]-4-(2H-tetrazol-5-yl)butanoic acid
Synonym	More Synonyms

Description	(R)-Plevitrexed ((R)-ZD 9331; (R)-BGC9331) is a less active enantiomer of Plevitrexed[1]. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor[2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Marsham PR, et al. Design and synthesis of potent non-polyglutamatable quinazoline antifolatethymidylate synthase inhibitors. J Med Chem. 1999 Sep 23;42(19):3809-20. [2]. Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem. 2013 Jul 11;56(13):5446-55.

Description

(R)-Plevitrexed ((R)-ZD 9331; (R)-BGC9331) is a less active enantiomer of Plevitrexed[1]. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor[2].

Related Catalog

Research Areas >> Others

Signaling Pathways >> Others >> Others

References

[1]. Marsham PR, et al. Design and synthesis of potent non-polyglutamatable quinazoline antifolatethymidylate synthase inhibitors. J Med Chem. 1999 Sep 23;42(19):3809-20.

[2]. Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem. 2013 Jul 11;56(13):5446-55.

Molecular Formula	C₂₆H₂₅FN₈O₄
Molecular Weight	532.52600
Exact Mass	532.19800
PSA	173.60000
LogP	2.63480

(2r)-2-[(2-fluoro-4-{[(4-hydroxy-2,7-dimethylquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}benzoyl)amino]-4-(2h-tetrazol-5-yl)butanoic acid

UNII-7PC8918P3Q

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (R)-Plevitrexed
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: (R)-Plevitrexed
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: (R)-Plevitrexed
Price: $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.