(R)-Plevitrexed

Modify Date: 2025-08-27 09:48:35

(R)-Plevitrexed Structure
(R)-Plevitrexed structure
Common Name (R)-Plevitrexed
CAS Number 153537-74-7 Molecular Weight 532.52600
Density N/A Boiling Point N/A
Molecular Formula C26H25FN8O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-Plevitrexed


(R)-Plevitrexed ((R)-ZD 9331; (R)-BGC9331) is a less active enantiomer of Plevitrexed[1]. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor[2].

 Names

Name (2R)-2-[[4-[(2,7-dimethyl-4-oxo-1H-quinazolin-6-yl)methyl-prop-2-ynylamino]-2-fluorobenzoyl]amino]-4-(2H-tetrazol-5-yl)butanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C26H25FN8O4
Molecular Weight 532.52600
Exact Mass 532.19800
PSA 173.60000
LogP 2.63480

 Synonyms

(2r)-2-[(2-fluoro-4-{[(4-hydroxy-2,7-dimethylquinazolin-6-yl)methyl](prop-2-yn-1-yl)amino}benzoyl)amino]-4-(2h-tetrazol-5-yl)butanoic acid
UNII-7PC8918P3Q
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