pralidoxime mesilate

Modify Date: 2026-06-30 12:03:00

pralidoxime mesilate structure	Common Name	pralidoxime mesilate
	CAS Number	154-97-2	Molecular Weight	232.25700
	Density	N/A	Boiling Point	189.7ºC at 760mmHg
	Molecular Formula	C₈H₁₂N₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	68.5ºC

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	pralidoxime mesylate
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Boiling Point	189.7ºC at 760mmHg
Molecular Formula	C₈H₁₂N₂O₄S
Molecular Weight	232.25700
Flash Point	68.5ºC
Exact Mass	232.05200
PSA	102.05000
LogP	0.56140

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

pralidoxime mesilate MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UU4570000

CHEMICAL NAME :: Pyridinium, 2-formyl-1-methyl-, methanesulfonate oxime

CAS REGISTRY NUMBER :: 154-97-2

LAST UPDATED :: 199512

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C7-H9-N2-O.C-H3-O3-S

MOLECULAR WEIGHT :: 232.28

WISWESSER LINE NOTATION :: T6KJ A1 B1UNQ &Q &OSW1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 52500 mg/kg/4W-I

TOXIC EFFECTS :: Gastrointestinal - other changes

REFERENCE :: AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 15,599,1967

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Vascular - BP elevation not characterized in autonomic section

REFERENCE :: AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 15,599,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CJBPAZ Canadian Journal of Biochemistry and Physiology. (Ottawa, Ont., Canada) V.32-41, 1954-63. For publisher information, see CJBIAE. Volume(issue)/page/year: 39,351,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 262 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 13,202,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 332 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 13,202,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 109 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 13,202,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CJBPAZ Canadian Journal of Biochemistry and Physiology. (Ottawa, Ont., Canada) V.32-41, 1954-63. For publisher information, see CJBIAE. Volume(issue)/page/year: 39,351,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 132 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 7,232,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 13,202,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 118 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 132,50,1961

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 356 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 13,202,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 118 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,559,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 258 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 33,559,1975 *** REVIEWS *** TOXICOLOGY REVIEW JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,1143,1964

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

2-Pyridinecarba...

CAS#:873-69-8

Methyl methanes...

CAS#:66-27-3

~88%

pralidoxime mesilate

CAS#:154-97-2

Learn More

Literature: Unnisa, Lateef; Sumakanth; Rao, B. Leelamaheswara; Divi, Murali Krishnaprasad; Rao, Mysore Aswathanarayana Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2014 , vol. 53, # 4 p. 431 - 435

Methyl methanes...

CAS#:66-27-3

PICOLINALDEHYDE...

CAS#:1193-96-0

pralidoxime mesilate

CAS#:154-97-2

Learn More

Literature: Journal of Pharmacy and Pharmacology, , vol. 11, p. 485 Biochemical Journal, , vol. 72, p. 70

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 3
CAS#:873-69-8 2-Pyridinecarba... CAS#:66-27-3 Methyl methanes... CAS#:1193-96-0 PICOLINALDEHYDE...
DownStream 1
CAS#:51-15-0 2-Pyridinealdox...

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

protopammethanesulfonate

pralidoximemethosulfate

2-(hydroxyimino-methyl)-1-methyl-pyridinium,methanesulfonate

contrathion

pralidoxime mesilate

pralidoxime methanesulphonate

pralidoximemesylate

Pralidoxime methylsulfate

2-(Hydroxyimino-methyl)-1-methyl-pyridinium,Methansulfonat

2-PYRIDINEALDOXIME METHYL METHANESULFONATE

Pralidoxime

p2s

pyridine-2-aldoxime methyl methanesulfonate

Einecs 205-839-8

2-pammethanesulfonate

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the molecular weight of pralidoxime mesylate?

A: Molecular weight of pralidoxime mesylate is 232.25700.

Q: What is the LogP of pralidoxime mesylate?

A: LogP of pralidoxime mesylate is 0.56140.

Q: What are the downstream products of pralidoxime mesylate?

A: Related downstream products(CAS) of pralidoxime mesylate: 51-15-0.

Q: What are the upstream materials of pralidoxime mesylate?

A: Related upstream materials(CAS) of pralidoxime mesylate: 873-69-8;66-27-3;1193-96-0.

Q: What is the boiling point of pralidoxime mesylate?

A: Boiling point of pralidoxime mesylate is 189.7ºC at 760mmHg.

Q: What are the storage conditions for pralidoxime mesylate?

A: Storage conditions for pralidoxime mesylate: 2-8℃。 .

Q: What English synonyms does pralidoxime mesylate have?

A: English synonyms of pralidoxime mesylate: protopammethanesulfonate, pralidoximemethosulfate, 2-(hydroxyimino-methyl)-1-methyl-pyridinium,methanesulfonate, contrathion, pralidoxime mesilate, pralidoxime methanesulphonate, pralidoximemesylate, Pralidoxime methylsulfate, 2-(Hydroxyimino-methyl)-1-methyl-pyridinium,Methansulfonat, 2-PYRIDINEALDOXIME METHYL METHANESULFONATE, Pralidoxime, p2s, pyridine-2-aldoxime methyl methanesulfonate, Einecs 205-839-8, 2-pammethanesulfonate.

Q: What is the molecular formula of pralidoxime mesylate?

A: Molecular formula of pralidoxime mesylate is C8H12N2O4S.

Q: What is the polar surface area (PSA) of pralidoxime mesylate?

A: Polar surface area (PSA) of pralidoxime mesylate is 102.05000.

Q: What is the English name of pralidoxime mesylate?

A: The English name of pralidoxime mesylate is pralidoxime mesylate.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Dayang Chem (Hangzhou) Co., Ltd.

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: pralidoxime mesilate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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pralidoxime mesilate

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