Pomalidomide-5-O-CH3
Modify Date: 2025-08-26 21:46:17
Pomalidomide-5-O-CH3 structure
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Common Name | Pomalidomide-5-O-CH3 | ||
|---|---|---|---|---|
| CAS Number | 1547163-02-9 | Molecular Weight | 303.27 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H13N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Pomalidomide-5-O-CH3Pomalidomide-5-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1]. |
| Name | Pomalidomide-5-O-CH3 |
|---|
| Description | Pomalidomide-5-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1]. |
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| Related Catalog | |
| Target |
Cereblon |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C14H13N3O5 |
|---|---|
| Molecular Weight | 303.27 |
| InChIKey | RSZICBZLAIFNKM-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(c1N)C(=O)N(C1CCC(=O)NC1=O)C2=O |
| Storage condition | 2-8°C |