Pomalidomide-6-O-CH3

Modify Date: 2024-01-17 13:03:13

Pomalidomide-6-O-CH3 structure	Common Name	Pomalidomide-6-O-CH3
	CAS Number	1547163-08-5	Molecular Weight	303.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₃N₃O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Pomalidomide-6-O-CH3

Pomalidomide-6-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1].

Name	Pomalidomide-6-O-CH3

Description	Pomalidomide-6-O-CH3 is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-O-CH3 can be connected to the ligand for protein by a linker to form PROTAC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> Ligand for E3 Ligase
Target	Cereblon
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Andrew J. Phillips, et al. Bromodomain targeting degronimers for target protein degradation. WO2017197056A1.

Molecular Formula	C₁₄H₁₃N₃O₅
Molecular Weight	303.27
Storage condition	2-8°C

DC Chemicals Limited
China
Product Name: Pomalidomide-6-O-CH3
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Cao

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