(3R,5S)-Fluvastatin

Modify Date: 2026-08-28 19:47:02

(3R,5S)-Fluvastatin Structure
(3R,5S)-Fluvastatin structure
Common Name (3R,5S)-Fluvastatin
CAS Number 155229-75-7 Molecular Weight 433.44800
Density 1.23 Boiling Point 681.8ºC at 760 mmHg
Molecular Formula C24H26FNO4 Melting Point N/A
MSDS N/A Flash Point 366.1ºC

 Use of (3R,5S)-Fluvastatin


(3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name (+)-3r,5s-fluvastatin sodium salt

 (3R,5S)-Fluvastatin Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description (3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
Related Catalog
References

[1]. Araújo FA, Rocha MA, Capettini LS, et al. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (fluvastatin) decreases inflammatory angiogenesis in mice. APMIS. 2012 24.

[2]. Makabe S, Takahashi Y, Watanabe H, et al. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. Atherosclerosis. 2010 Dec;213(2):377-84.

[3]. Scripture CD, Pieper JA. Clinical pharmacokinetics of fluvastatin. Clin Pharmacokinet. 2001;40(4):263-81.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.23
Boiling Point 681.8ºC at 760 mmHg
Molecular Formula C24H26FNO4
Molecular Weight 433.44800
Flash Point 366.1ºC
Exact Mass 433.16700
PSA 85.52000
LogP 3.29340

 (3R,5S)-Fluvastatin | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the English name of (+)-3r,5s-fluvastatin sodium salt?
A: The English name of (+)-3r,5s-fluvastatin sodium salt is (+)-3r,5s-fluvastatin sodium salt.
Q: What is the polar surface area (PSA) of (+)-3r,5s-fluvastatin sodium salt?
A: Polar surface area (PSA) of (+)-3r,5s-fluvastatin sodium salt is 85.52000.
Q: What is the LogP of (+)-3r,5s-fluvastatin sodium salt?
A: LogP of (+)-3r,5s-fluvastatin sodium salt is 3.29340.
Q: What is the CAS number of (+)-3r,5s-fluvastatin sodium salt?
A: CAS number of (+)-3r,5s-fluvastatin sodium salt is 155229-75-7.
Q: What are the uses of (+)-3r,5s-fluvastatin sodium salt?
A: Main uses of (+)-3r,5s-fluvastatin sodium salt: (3R,5S)-Fluvastatin is the 3R,5S-isomer Fluvastatin. Fluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1][2][3].
Q: What is the molecular weight of (+)-3r,5s-fluvastatin sodium salt?
A: Molecular weight of (+)-3r,5s-fluvastatin sodium salt is 433.44800.
Q: What is the molecular formula of (+)-3r,5s-fluvastatin sodium salt?
A: Molecular formula of (+)-3r,5s-fluvastatin sodium salt is C24H26FNO4.
Q: What is the boiling point of (+)-3r,5s-fluvastatin sodium salt?
A: Boiling point of (+)-3r,5s-fluvastatin sodium salt is 681.8ºC at 760 mmHg.

 (3R,5S)-Fluvastatinfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

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