5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl

Modify Date: 2025-10-08 08:34:05

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure
5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl structure
Common Name 5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl
CAS Number 15601-44-2 Molecular Weight 283.70900
Density 1.27g/cm3 Boiling Point 420.2ºC at 760mmHg
Molecular Formula C16H10ClNO2 Melting Point N/A
MSDS N/A Flash Point 207.9ºC

 Names

Name (E,Z)-4-(4-chlorobenzylidene)-2-phenyl-4,5-dihydrooxazol-5-one

 Chemical & Physical Properties

Density 1.27g/cm3
Boiling Point 420.2ºC at 760mmHg
Molecular Formula C16H10ClNO2
Molecular Weight 283.70900
Flash Point 207.9ºC
Exact Mass 283.04000
PSA 38.66000
LogP 3.12010
Vapour Pressure 2.87E-07mmHg at 25°C
Index of Refraction 1.623
InChIKey PKMDOGQJFLVZEJ-UVTDQMKNSA-N
SMILES O=C1OC(c2ccccc2)=NC1=Cc1ccc(Cl)cc1

 Synthetic Route

~93%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Madje, Balaji; Ubale, Milind; Bharad, Jagdish; Shingare, Murlidhar Journal of the Indian Chemical Society, 2012 , vol. 89, # 9 p. 1295 - 1299

~93%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Khosropour, Ahmad R.; Khodaei, Mohammad M.; Hoseini Jomor, Seyed J. Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 3 p. 683 - 686

~88%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Rostami, Mahboubeh; Khosropour, Ahmad Reza; Mirkhani, Valiollah; Mohammadpoor-Baltork, Iraj; Moghadam, Majid; Tangestaninejad, Shahram Monatshefte fur Chemie, 2011 , vol. 142, # 11 p. 1175 - 1180

~97%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Abdel-Motaleb, Ramadan M.; Bakeer, Hadeer M.; Tamam, Gammal H.; Arafa, Wael A. A. Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 5 p. 1071 - 1076,6

~%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Hemasrilatha; Sruthi; Manjula; Harinadha Babu; Vittal Rao Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 7 p. 981 - 987

~66%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Tikdari; Fozooni; Vazee; Hamidian Russian Journal of Organic Chemistry, 2005 , vol. 41, # 7 p. 1046 - 1049

~%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

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Literature: Kidwai; Kumar Organic Preparations and Procedures International, 1998 , vol. 30, # 4 p. 451 - 453

~%

5(4H)-Oxazolone,4-[(4-chlorophenyl)methylene]-2-phenyl Structure

5(4H)-Oxazolone...

CAS#:15601-44-2

Learn More
Literature: Hamidian, Hooshang; Tikdari, Ahmad Momeni; Khabazzadeh, Hojatollah Molecules, 2006 , vol. 11, # 5 p. 377 - 382

 Bioassay

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Name: Dicer-mediated maturation of pre-microRNA
Source: Center for Chemical Genomics, University of Michigan
Target: N/A
External Id: TargetID_659_CEMA
Name: Alphascreen assay for small molecules abrogating mHTT-CaM Interaction
Source: 24983
Target: Huntingtin
External Id: KUHTS-Muma KU-CaM-Htt INH-01
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