zoxamide

Modify Date: 2024-01-02 16:54:00

zoxamide Structure
zoxamide structure
Common Name zoxamide
CAS Number 156052-68-5 Molecular Weight 336.64
Density 1.3±0.1 g/cm3 Boiling Point 415.4±45.0 °C at 760 mmHg
Molecular Formula C14H16Cl3NO2 Melting Point 159.5-161ºC
MSDS Chinese USA Flash Point 205.0±28.7 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of zoxamide


Zoxamide (RH-7281) is an oomycete fungicide. Zoxamide arrests nuclear division in Phytophthora capsici germlings and destroyed the microtubule cytoskeleton[1][2].

 Names

Name zoxamide
Synonym More Synonyms

 zoxamide Biological Activity

Description Zoxamide (RH-7281) is an oomycete fungicide. Zoxamide arrests nuclear division in Phytophthora capsici germlings and destroyed the microtubule cytoskeleton[1][2].
Related Catalog
References

[1]. Mei X, et al. Proteomic analysis on zoxamide-induced sensitivity changes in Phytophthora cactorum. Pestic Biochem Physiol. 2015 Sep;123:9-18.  

[2]. David H. Young, et al. Mode of Action of Zoxamide (RH-7281), a New Oomycete Fungicide. Pesticide Biochemistry and Physiology. Volume 69, Issue 2, February 2001, Pages 100-111.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 415.4±45.0 °C at 760 mmHg
Melting Point 159.5-161ºC
Molecular Formula C14H16Cl3NO2
Molecular Weight 336.64
Flash Point 205.0±28.7 °C
Exact Mass 335.024658
PSA 46.17000
LogP 4.84
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.545

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H317-H319-H410
Precautionary Statements P273-P280-P305 + P351 + P338-P333 + P313-P391-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
RIDADR UN 3077 9 / PGIII

 Synthetic Route

~89%

zoxamide Structure

zoxamide

CAS#:156052-68-5

Literature: ROHM AND HAAS COMPANY Patent: EP952143 A1, 1999 ;

 Precursor & DownStream

Precursor  1

DownStream  0

 Articles2

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Resistance to the novel fungicide pyrimorph in Phytophthora capsici: risk assessment and detection of point mutations in CesA3 that confer resistance.

PLoS ONE 8 , e56513, (2013)

Pyrimorph is a novel fungicide with high activity against the plant pathogen Phytophthora capsici. We investigated the risk that P. capsici can develop resistance to pyrimorph. The baseline sensitivit...

 Synonyms

3,5-Dichloro-N-(1-chloro-3-methyl-2-oxopentan-3-yl)-4-methylbenzamide
N-[3'-(1'-chloro-3'-methyl-2'-oxopentan)]-3,5-dichloro-4-methylbenzamide
rac-3,5-dichloro-N-[(3R)-1-chloro-3-methyl-2-oxopentan-3-yl]-4-methylbenzamide
3,5-Dichloro-N-(1-chloro-3-methyl-2-oxo-3-pentanyl)-4-methylbenzamide
3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxo-propyl)-4-methyl-benzamide
zoxamide
Zoxamid
3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide
3,5-dichloro-N-(3-chloro-l-ethyl-l-methyl-2-oxopropyl)-4-methylbenzamide
(S)-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-3.5-dichloro-4-methylbenzamide
Zoxium
rh-7281
3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-4-methylbenzamide
Benzamide, 3,5-dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-4-methyl-
(RS)-3,5-Dichloro-N-(3-chloro-1-ethyl-1-methyl-2-oxopropyl)-p-toluamide
N-(1-chloro-3-methyl-2-oxopent-3-yl)-3,5-dichloro-4-methylbenzamide