Thymine-d4-1
Modify Date: 2024-01-02 05:41:45
Thymine-d4-1 structure
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Common Name | Thymine-d4-1 | ||
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| CAS Number | 156054-85-2 | Molecular Weight | 130.13800 | |
| Density | 1.266g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C5H2D4N2O2 | Melting Point | 325-327ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Thymine-d4-1Thymine-d4-1 is the deuterium labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2]. |
| Name | 6-deuterio-5-(trideuteriomethyl)-1H-pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
| Description | Thymine-d4-1 is the deuterium labeled Thymine[1]. Thymine is one of the four nucleobases in the nucleic acid of DNA and can be a target for actions of 5-fluorouracil (5-FU) in cancer treatment, with a Km of 2.3 μM[2]. |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.266g/cm3 |
|---|---|
| Melting Point | 325-327ºC(lit.) |
| Molecular Formula | C5H2D4N2O2 |
| Molecular Weight | 130.13800 |
| Exact Mass | 130.06800 |
| PSA | 58.53000 |
| Index of Refraction | 1.489 |
| RIDADR | NONH for all modes of transport |
|---|---|
| WGK Germany | 3 |
| Thymine-methyl-d3-6-d |
| MFCD01075460 |