PYD-106
Modify Date: 2024-01-02 22:22:43
PYD-106 structure
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Common Name | PYD-106 | ||
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| CAS Number | 1560894-05-4 | Molecular Weight | 432.469 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 723.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C25H24N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 391.0±32.9 °C | |
Use of PYD-106PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and glycine EC50. PYD-106 selectively enhances the responses of diheteromeric GluN1/GluN2C receptors but not triheteromeric GluN1/GluN2A/GluN2C receptors[1]. |
| Name | PYD-106 |
|---|---|
| Synonym | More Synonyms |
| Description | PYD-106 is a stereoselective pyrrolidinone (PYD) positive allosteric modulator for GluN2C-containing NMDA receptors. PYD-106 increases opening frequency and open time of single channel currents activated by maximally effective concentrations of agonist but only has modest effects on glutamate and glycine EC50. PYD-106 selectively enhances the responses of diheteromeric GluN1/GluN2C receptors but not triheteromeric GluN1/GluN2A/GluN2C receptors[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 723.0±60.0 °C at 760 mmHg |
| Molecular Formula | C25H24N2O5 |
| Molecular Weight | 432.469 |
| Flash Point | 391.0±32.9 °C |
| Exact Mass | 432.168518 |
| LogP | 3.45 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.663 |
| PYD-106 |
| Benzoic acid, 4-[3-acetyl-2,5-dihydro-4-hydroxy-1-[2-(2-methyl-1H-indol-3-yl)ethyl]-5-oxo-1H-pyrrol-2-yl]-, methyl ester |
| Methyl 4-{3-acetyl-4-hydroxy-1-[2-(2-methyl-1H-indol-3-yl)ethyl]-5-oxo-2,5-dihydro-1H-pyrrol-2-yl}benzoate |