UU-T03

Modify Date: 2024-09-12 14:17:56

UU-T03 Structure
UU-T03 structure
Common Name UU-T03
CAS Number 1586007-00-2 Molecular Weight 721.204
Density N/A Boiling Point N/A
Molecular Formula C37H41ClN4O9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UU-T03


UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells.

 Names

Name UU-T03

 UU-T03 Biological Activity

Description UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells.
References References 1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201. View Related Products by Target Beta-catenin

 Chemical & Physical Properties

Molecular Formula C37H41ClN4O9
Molecular Weight 721.204
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