1586007-00-2
1586007-00-2 structure
- Name: UU-T03
- Chemical Name: UU-T03
- CAS Number: 1586007-00-2
- Molecular Formula: C37H41ClN4O9
- Molecular Weight: 721.204
- Create Date: 2020-01-20 07:42:57
- Modify Date: 2024-09-12 14:17:56
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UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells.
| Name | UU-T03 |
|---|
| Description | UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates the transcription of AXIN2, LGR5, cyclin D1, and c-Myc in dose-dependent manners in SW480 cells. |
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| References | References 1. Huang Z, et al. ACS Chem Biol. 2014 Jan 17;9(1):193-201. View Related Products by Target Beta-catenin |
| Molecular Formula | C37H41ClN4O9 |
|---|---|
| Molecular Weight | 721.204 |