![]() Collismycin A structure
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Common Name | Collismycin A | ||
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CAS Number | 158792-24-6 | Molecular Weight | 275.32600 | |
Density | 1.27g/cm3 | Boiling Point | 381.2ºC at 760 mmHg | |
Molecular Formula | C13H13N3O2S | Melting Point | N/A | |
MSDS | N/A | Flash Point | 184.3ºC |
Use of Collismycin ACollismycin A is a bacterial metabolite with antibacterial, antiproliferative, and neuroprotective properties. It is active against a variety of bacteria and fungi. It inhibits proliferation of A549 lung, HCT116 colon, HeLa cervical cancer cells, and NIH373 fibroblasts but not MDA-MD-231 breast cancer cells. Collismycin A forms a complex with Fe(II) and Fe(III) at a 2:1 ratio, and the addition of iron ions inhibits the antiproliferative effect of collismycin A on HeLa cells, an effect that does not occur with the addition of zinc, manganese, copper, or magnesium ions. Collismycin A (1 μM) prevents apoptosis in the brain region of zebrafish larvae by 44% in a model of neuronal cell death induced by all-trans retinoic acid. |
Name | (2E)-4-methoxy-3-methylsulfanyl-2-(nitrosomethylidene)-6-pyridin-2-yl-1H-pyridine |
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Synonym | More Synonyms |
Density | 1.27g/cm3 |
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Boiling Point | 381.2ºC at 760 mmHg |
Molecular Formula | C13H13N3O2S |
Molecular Weight | 275.32600 |
Flash Point | 184.3ºC |
Exact Mass | 275.07300 |
PSA | 92.90000 |
LogP | 2.68220 |
Vapour Pressure | 5.16E-06mmHg at 25°C |
Index of Refraction | 1.624 |
HS Code | 2933399090 |
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HS Code | 2933399090 |
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Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
(E)-4-Methoxy-5-(methylthio)-[2,2'-bipyridine]-6-carbaldehyde oxime |
(2,2'-Bipyridine)-6-carboxaldehyde,4-methoxy-5-(methylthio)-,oxime,(E) |
4-methoxy-5-methylsulfanyl-[2,2']bipyridinyl-6-carbaldehyde oxime |
(E)-4-methoxy-5-(methylthio)-[2,2'-bipyridine]-6-carboxaldehyde oxime |
Collismycin A |