Fmoc-Aad(otBu)-OH

Modify Date: 2026-07-12 17:08:12

Fmoc-Aad(otBu)-OH Structure
Fmoc-Aad(otBu)-OH structure
Common Name Fmoc-Aad(otBu)-OH
CAS Number 159751-47-0 Molecular Weight 439.50100
Density 1.214g/cm3 Boiling Point 625.5ºC at 760mmHg
Molecular Formula C25H29NO6 Melting Point 108-112ºC
MSDS N/A Flash Point 332.1ºC

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid
Synonym More Synonyms

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 1.214g/cm3
Boiling Point 625.5ºC at 760mmHg
Melting Point 108-112ºC
Molecular Formula C25H29NO6
Molecular Weight 439.50100
Flash Point 332.1ºC
Exact Mass 439.19900
PSA 101.93000
LogP 4.88120
Vapour Pressure 1.64E-16mmHg at 25°C
Index of Refraction 1.566
InChIKey FFLAQPKWVSSKJC-NRFANRHFSA-N
SMILES CC(C)(C)OC(=O)CCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: Fmoc-Aad(otBu)-OH
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Fmoc-Aad(otBu)-OH
CAS number:159751-47-0

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Store in closed vessels, refrigerated.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C25H29NO6
Molecular weight:439.5

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Hazard Codes Xi

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  4

DownStream  0

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

(S)-2-Fmoc-aminohexanedioic acid 6-tert-butyl ester
Fmoc-Aad(OtBu)
(S)-2-Fmoc-Aminohexanedioic acid 6-tert-butyl ester
(S)-2-[((9H-fluoren-9-yl)methoxy)carbonylamino]-6-tert-butoxy-6-oxohexanoic acid
(S)-2-(Fmoc-Amino)-Hexanedioic Acid-6-T-Butyl Ester
Fmoc-Aad(tBu)-OH
Fmoc-Aad(Otbu)-OH
Fmoc-β-homo-Glu(OtBu)-OH

 Fmoc-Aad(otBu)-OH | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: SMILES notation of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is CC(C)(C)OC(=O)CCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O.
Q: What is the LogP of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: LogP of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is 4.88120.
Q: What English synonyms does (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid have?
A: English synonyms of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid: (S)-2-Fmoc-aminohexanedioic acid 6-tert-butyl ester, Fmoc-Aad(OtBu), (S)-2-Fmoc-Aminohexanedioic acid 6-tert-butyl ester, (S)-2-[((9H-fluoren-9-yl)methoxy)carbonylamino]-6-tert-butoxy-6-oxohexanoic acid, (S)-2-(Fmoc-Amino)-Hexanedioic Acid-6-T-Butyl Ester, Fmoc-Aad(tBu)-OH, Fmoc-Aad(Otbu)-OH, Fmoc-β-homo-Glu(OtBu)-OH.
Q: What is the melting point of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: Melting point of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is 108-112ºC.
Q: What is the InChIKey of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: InChIKey of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is FFLAQPKWVSSKJC-NRFANRHFSA-N.
Q: What is the boiling point of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: Boiling point of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is 625.5ºC at 760mmHg.
Q: What is the molecular formula of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: Molecular formula of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is C25H29NO6.
Q: What are the upstream materials of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: Related upstream materials(CAS) of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid: 868754-93-2;1663-39-4;146549-21-5;477578-53-3.
Q: What is the polar surface area (PSA) of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: Polar surface area (PSA) of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is 101.93000.
Q: What is the CAS number of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid?
A: CAS number of (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxy]-6-oxohexanoic acid is 159751-47-0.

 Fmoc-Aad(otBu)-OHfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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