L-Methionine-DL-sulfoximine

Modify Date: 2024-01-02 10:47:15

L-Methionine-DL-sulfoximine Structure
L-Methionine-DL-sulfoximine structure
Common Name L-Methionine-DL-sulfoximine
CAS Number 15985-39-4 Molecular Weight 180.225
Density 1.5±0.1 g/cm3 Boiling Point 352.2±52.0 °C at 760 mmHg
Molecular Formula C5H12N2O3S Melting Point >210ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 166.8±30.7 °C

 Use of L-Methionine-DL-sulfoximine


L-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia.

 Names

Name L-methionine sulfoximine
Synonym More Synonyms

 L-Methionine-DL-sulfoximine Biological Activity

Description L-Methionine-DL-sulfoximine (MSX) is an inhibitor of glutamine synthetase. L-Methionine-DL-sulfoximine is also a potent convulsant which metabolically and morphologically primarily affects astroglia.
Related Catalog
References

[1]. Albrecht J, Norenberg MD. L-methionine-DL-sulfoximine induces massive efflux of glutamine from cortical astrocytes in primary culture. Eur J Pharmacol. 1990;182(3):587-589.

[2]. Premakumar R, Sorger GJ, Gooden D. Repression of nitrate reductase in Neurospora studied by using L-methionine-DL-sulfoximine and glutamine auxotroph gln-1b. J Bacteriol. 1980;143(1):411-415.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 352.2±52.0 °C at 760 mmHg
Melting Point >210ºC (dec.)(lit.)
Molecular Formula C5H12N2O3S
Molecular Weight 180.225
Flash Point 166.8±30.7 °C
Exact Mass 180.056870
PSA 112.62000
LogP -1.38
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.560
Storage condition 0-6°C
Stability Temperature Sensitive

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925290090

 Precursor & DownStream

Precursor  0

DownStream  2

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

Butanoic acid, 2-amino-4-(S-methylsulfonimidoyl)-, (2S)-
L-S-(3-Amino-3-carboxypropyl)-S-methylsulfoximine
2-Amino-4-(S-methylsulfonimidoyl)butanoic acid
MFCD00002621
UNII:M9P6YZ6JX9
(2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic acid
L-Methionine sulfoximine
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