NIBR 189
Modify Date: 2025-08-27 21:00:17
NIBR 189 structure
|
Common Name | NIBR 189 | ||
|---|---|---|---|---|
| CAS Number | 1599432-08-2 | Molecular Weight | 429.30700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H21BrN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NIBR 189NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).IC50 value: 16/11 nM(Binding/Functional IC50) [1]Target: EBI2/GPR183 antagonistNIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease. |
| Name | nibr-189 |
|---|---|
| Synonym | More Synonyms |
| Description | NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).IC50 value: 16/11 nM(Binding/Functional IC50) [1]Target: EBI2/GPR183 antagonistNIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C21H21BrN2O3 |
|---|---|
| Molecular Weight | 429.30700 |
| Exact Mass | 428.07400 |
| PSA | 49.85000 |
| LogP | 3.33130 |
| Storage condition | 2-8℃ |
| (E)-3-(4-bromophenyl)-1-(4-(4-methoxybenzoyl)piperazin-1-yl)prop-2-en-1-one |
| NIBR189 |