1-(3-Methoxyphenyl)piperazine

Modify Date: 2026-07-02 10:24:44

1-(3-Methoxyphenyl)piperazine Structure
1-(3-Methoxyphenyl)piperazine structure
Common Name 1-(3-Methoxyphenyl)piperazine
CAS Number 16015-71-7 Molecular Weight 192.258
Density 1.1±0.1 g/cm3 Boiling Point 344.0±27.0 °C at 760 mmHg
Molecular Formula C11H16N2O Melting Point 201-204°C
MSDS Chinese USA Flash Point 161.8±23.7 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 1-(3-Methoxyphenyl)piperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 344.0±27.0 °C at 760 mmHg
Melting Point 201-204°C
Molecular Formula C11H16N2O
Molecular Weight 192.258
Flash Point 161.8±23.7 °C
Exact Mass 192.126266
PSA 24.50000
LogP 1.01
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.534
InChIKey PZIBVWUXWNYTNL-UHFFFAOYSA-N
SMILES COc1cccc(N2CCNCC2)c1

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive;
Risk Phrases R34
Safety Phrases S26-S27-S36/37/39-S45
RIDADR UN 3267 8/PG 3
WGK Germany 3
HS Code 2933599090

 Synthetic Route

~89%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Tetrahedron, , vol. 58, # 34 p. 6913 - 6924

~86%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Brenner, Eric; Schneider, Raphael; Fort, Yves Tetrahedron Letters, 2000 , vol. 41, # 16 p. 2881 - 2884

~93%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Liu, Kevin G.; Robichaud, Albert J. Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7921 - 7922

~49%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Zhao, Shu-Hai; Miller, Aubry K.; Berger, Jacob; Flippin, Lee A. Tetrahedron Letters, 1996 , vol. 37, # 26 p. 4463 - 4466

~%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Tetrahedron Letters, , vol. 39, # 7 p. 617 - 620

~%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Tetrahedron Letters, , vol. 39, # 7 p. 617 - 620

~%

Detail Learn More
Literature: Tetrahedron Letters, , vol. 39, # 7 p. 617 - 620

~%

1-(3-Methoxyphenyl)piperazine Structure

1-(3-Methoxyphe...

CAS#:16015-71-7

Learn More
Literature: Tetrahedron Letters, , vol. 37, # 47 p. 8487 - 8488

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

More Articles
N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed. Caccia S.

Curr. Drug Metab. 8(6) , 612-22, (2007)

 1-(3-Methoxyphenyl)piperazineBioassay

View more

Name: Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, ...
Source: ChEMBL
Target: Beta-1 adrenergic receptor
External Id: CHEMBL654268
Name: Displacement of [3H]2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryp...
Source: ChEMBL
Target: 5-hydroxytryptamine receptor 1A
External Id: CHEMBL615958
Name: Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenol...
Source: ChEMBL
Target: Beta-2 adrenergic receptor
External Id: CHEMBL655998
Total 3, Current Page 1 of 1
1

 Synonyms

N-(3-methoxyphenyl)-piperazine
EINECS 240-154-8
1-(3-methoxyphenyl)-piperazine
1-(m-methoxyphenyl)piperazine
3-methoxy-1-piperazinylbenzene
(3-methoxyphenyl)piperazine
MFCD00040733
3-(1-piperazinyl)anisole
4-(3-methoxyphenyl)piperazine
1-(3-Methoxyphenyl)piperazine
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