3-Methylpyridin-2-amine

Modify Date: 2024-01-02 17:21:33

3-Methylpyridin-2-amine structure	Common Name	3-Methylpyridin-2-amine
	CAS Number	1603-40-3	Molecular Weight	108.141
	Density	1.1±0.1 g/cm3	Boiling Point	220.9±20.0 °C at 760 mmHg
	Molecular Formula	C₆H₈N₂	Melting Point	29-31 °C(lit.)
	MSDS	Chinese USA	Flash Point	111.7±0.0 °C
	Symbol	GHS06, GHS08	Signal Word	Danger

Name	2-Amino-3-picoline
Synonym	More Synonyms

Density	1.1±0.1 g/cm3
Boiling Point	220.9±20.0 °C at 760 mmHg
Melting Point	29-31 °C(lit.)
Molecular Formula	C₆H₈N₂
Molecular Weight	108.141
Flash Point	111.7±0.0 °C
Exact Mass	108.068748
PSA	38.91000
LogP	1.08
Vapour Pressure	0.1±0.4 mmHg at 25°C
Index of Refraction	1.574
Water Solubility	SOLUBLE

3-Methylpyridin-2-amine MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US1850000

CHEMICAL NAME :: Pyridine, 2-amino-3-methyl-

CAS REGISTRY NUMBER :: 1603-40-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C6-H8-N2

MOLECULAR WEIGHT :: 108.16

WISWESSER LINE NOTATION :: T6NJ BZ C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 650 ppm/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 36 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: AJEBAK Australian Journal of Experimental Biology and Medical Science. (Adelaide, S.A., Australia) V.1-64, 1924-86. Volume(issue)/page/year: 36,491,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01585

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,841,1986

Symbol	GHS06, GHS08
Signal Word	Danger
Hazard Statements	H301-H311-H331-H373
Precautionary Statements	P261-P280-P301 + P310-P311
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R25;R36/37/38
Safety Phrases	S36/37/39-S45-S37/39-S28A-S26
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	US1850000
Packaging Group	II
Hazard Class	6.1
HS Code	29333999

2-Bromo-3-methy...

CAS#:3430-17-9

~98%

3-Methylpyridin...

CAS#:1603-40-3

Literature: Elmkaddem, Mohammed K.; Fischmeister, Cedric; Thomas, Christophe M.; Renaud, Jean-Luc Chemical Communications, 2010 , vol. 46, # 6 p. 925 - 927

2-Chloro-3-picoline

CAS#:18368-76-8

3-Methylpyridin...

CAS#:1603-40-3

3-methyl-N-(3-m...

CAS#:6654-69-9

Literature: Organic Letters, , vol. 15, # 14 p. 3734 - 3737

3-picoline n-oxide

CAS#:1003-73-2

2-Amino-5-methy...

CAS#:1603-41-4

3-Methylpyridin...

CAS#:1603-40-3

Literature: Journal of Organic Chemistry, , vol. 72, # 12 p. 4554 - 4557

2-Chloro-3-picoline

CAS#:18368-76-8

3-Methylpyridin...

CAS#:1603-40-3

Literature: Chemistry - A European Journal, , vol. 16, # 6 p. 1983 - 1991

3-Mepy

CAS#:108-99-6

3-Methylpyridin...

CAS#:1603-40-3

Literature: Chemische Berichte, , vol. 57, p. 1804 Chemische Berichte, , vol. 58, p. 1733

3-picoline n-oxide

CAS#:1003-73-2

3-Methylpyridin...

CAS#:1603-40-3

Literature: Bioorganic and medicinal chemistry letters, , vol. 10, # 17 p. 1975 - 1978

3-Mepy

CAS#:108-99-6

2-Amino-5-methy...

CAS#:1603-41-4

3-Methylpyridin...

CAS#:1603-40-3

Literature: US2456379 , ;

Precursor 4
CAS#:3430-17-9 2-Bromo-3-methy... CAS#:18368-76-8 2-Chloro-3-picoline CAS#:1003-73-2 3-picoline n-oxide CAS#:108-99-6 3-Mepy
DownStream 10
CAS#:3430-17-9 2-Bromo-3-methy... CAS#:5654-97-7 1,3-Dihydro-2H-... CAS#:40741-48-8 6-amino-5-methy... CAS#:3430-18-0 2,5-Dibromo-3-m...
CAS#:42959-38-6 2-Chloro-5-nitr... CAS#:364-22-7 3-Pyridinecarbo... CAS#:407-21-6 3-Fluoro-5-picoline CAS#:5654-95-5 1H-Pyrrolo[2,3-...
CAS#:3430-19-1 3-Amino-5-methy... CAS#:3430-21-5 2-Amino-5-bromo...

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synthesis and characterisation of two novel proton transfer compounds and their inhibition studies on carbonic anhydrase isoenzymes.

J. Enzyme Inhib. Med. Chem. 26(1) , 104-14, (2011)

Two novel proton transfer compounds were prepared between 2,4-dichloro-5-sulphamoylbenzoic acid (lasamide) (Hsba) and ethylenediamine (en), namely ethane-1,2-diaminium 2,4-dichloro-5-sulphamoylbenzoat...

Comutagenesis-III. In vitro metabolism of 2-amino-3-methylpyridine: the effect of various potential inhibitors, activators and inducers.

Xenobiotica 27(11) , 1103-11, (1997)

1. The effects of various potential inhibitors, activators and inducers on the metabolism of the comutagen 2-amino-3-methylpyridine (2A3MP) by rabbit hepatic microsomes and S9 supernatants have been s...

Comutagenesis-I: the in vitro metabolism of 2-amino-3-methylpyridine.

Anticancer Res. 17(5A) , 3485-91, (1997)

The metabolism of the comutagen 2-amino-3-methylpyridine has been studied in vitro using rat and rabbit hepatic preparations. 2-Amino-3-methylpyridine-N-oxide, 2-amino-3-hydroxymethylpyridine and 2-am...

MFCD00006320

3-methylpyridin-2-amine

2-Pyridinamine, 3-methyl-

2-Amino-3-picoline

3-Methyl-2-pyridinamine

3-Methylpyridin-2-amin

EINECS 216-501-4

2-Amino-3-methylpyridine

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 3-Methylpyridin-2-amine
Price: ￥468.0/500g ￥138.0/100g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Amino-3-Methylpyridine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-Amino-3-picoline
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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3-Methylpyridin-2-amine

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